Valbazen
Brand names,
Valbazen
Analogs
Valbazen
Brand Names Mixture
Valbazen
Chemical_Formula
C12H15N3O2S
Valbazen
RX_link
http://www.rxlist.com/cgi/generic2/albendazole.htm
Valbazen
fda sheet
Valbazen
msds (material safety sheet)
Valbazen
Synthesis Reference
No information avaliable
Valbazen
Molecular Weight
265.333 g/mol
Valbazen
Melting Point
209 oC
Valbazen
H2O Solubility
Practically insoluble
Valbazen
State
Solid
Valbazen
LogP
3.299
Valbazen
Dosage Forms
Suspension; Tablets (200mg)
Valbazen
Indication
For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.
Valbazen
Pharmacology
Albendazole is a broad-spectrum anthelmintic. The principal mode of action for albendazole is by its inhibitory effect on tubulin polymerization which results in the loss of cytoplasmic microtubules.
Valbazen
Absorption
Poorly absorbed from the gastrointestinal tract due to its low aqueous solubility. Oral bioavailability appears to be enhanced when coadministered with a fatty meal (estimated fat content 40 g)
Valbazen
side effects and Toxicity
Symptoms of overdose include elevated liver enzymes, headaches, hair loss, low levels of white blood cells (neutropenia), fever, and itching.
Valbazen
Patient Information
Valbazen
Organisms Affected
Helminthic Microorganisms