Albenza
Brand names,
Albenza
Analogs
Albenza
Brand Names Mixture
Albenza
Chemical_Formula
C12H15N3O2S
Albenza
RX_link
http://www.rxlist.com/cgi/generic2/albendazole.htm
Albenza
fda sheet
Albenza
msds (material safety sheet)
Albenza
Synthesis Reference
No information avaliable
Albenza
Molecular Weight
265.333 g/mol
Albenza
Melting Point
209 oC
Albenza
H2O Solubility
Practically insoluble
Albenza
State
Solid
Albenza
LogP
3.299
Albenza
Dosage Forms
Suspension; Tablets (200mg)
Albenza
Indication
For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.
Albenza
Pharmacology
Albendazole is a broad-spectrum anthelmintic. The principal mode of action for albendazole is by its inhibitory effect on tubulin polymerization which results in the loss of cytoplasmic microtubules.
Albenza
Absorption
Poorly absorbed from the gastrointestinal tract due to its low aqueous solubility. Oral bioavailability appears to be enhanced when coadministered with a fatty meal (estimated fat content 40 g)
Albenza
side effects and Toxicity
Symptoms of overdose include elevated liver enzymes, headaches, hair loss, low levels of white blood cells (neutropenia), fever, and itching.
Albenza
Patient Information
Albenza
Organisms Affected
Helminthic Microorganisms