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Adapalene Brand names, Adapalene Analogs

Adapalene Brand Names Mixture

  • No information avaliable

Adapalene Chemical_Formula


Adapalene RX_link

Adapalene fda sheet

Adapalene FDA

Adapalene msds (material safety sheet)

Adapalene MSDS

Adapalene Synthesis Reference

No information avaliable

Adapalene Molecular Weight

412.52 g/mol

Adapalene Melting Point

No information avaliable

Adapalene H2O Solubility

Practically Insoluble

Adapalene State


Adapalene LogP


Adapalene Dosage Forms

Gel (0.1%); Solution; Pledglets; Cream

Adapalene Indication

For the topical treatment of comedo, papular and pustular acne (acne vulgaris) of the face, chest or back.

Adapalene Pharmacology

Adapalene is a chemically stable retinoid-like compound. Biochemical and pharmacological profile studies have demonstrated that adapalene is a modulator of cellular differentiation, keratinization, and inflammatory processes all of which represent important features in the pathology of acne vulgaris.

Adapalene Absorption

Absorption of adapalene through human skin is low. Only trace amounts (<0.25 ng/mL) of parent substance have been found in the plasma of acne patients following chronic topical application of adapalene in controlled clinical trials

Adapalene side effects and Toxicity

The acute oral toxicity of adapalene in mice and rats is greater than 10 mL/kg. Chronic ingestion of the drug may lead to the same side effects as those associated with excessive oral intake of Vitamin A.

Adapalene Patient Information

Adapalene Organisms Affected

Humans and other mammals