Differin en es it fr

Differin Brand names, Differin Analogs

Differin Brand Names Mixture

  • No information avaliable

Differin Chemical_Formula


Differin RX_link


Differin fda sheet

Differin FDA

Differin msds (material safety sheet)

Differin MSDS

Differin Synthesis Reference

No information avaliable

Differin Molecular Weight

412.52 g/mol

Differin Melting Point

No information avaliable

Differin H2O Solubility

Practically Insoluble

Differin State


Differin LogP


Differin Dosage Forms

Gel (0.1%); Solution; Pledglets; Cream

Differin Indication

For the topical treatment of comedo, papular and pustular acne (acne vulgaris) of the face, chest or back.

Differin Pharmacology

Adapalene is a chemically stable retinoid-like compound. Biochemical and pharmacological profile studies have demonstrated that adapalene is a modulator of cellular differentiation, keratinization, and inflammatory processes all of which represent important features in the pathology of acne vulgaris.

Differin Absorption

Absorption of adapalene through human skin is low. Only trace amounts (<0.25 ng/mL) of parent substance have been found in the plasma of acne patients following chronic topical application of adapalene in controlled clinical trials

Differin side effects and Toxicity

The acute oral toxicity of adapalene in mice and rats is greater than 10 mL/kg. Chronic ingestion of the drug may lead to the same side effects as those associated with excessive oral intake of Vitamin A.

Differin Patient Information

Differin Organisms Affected

Humans and other mammals