Adagen (Enzon Inc.)
Adagen (Enzon Inc.) Brand names, Adagen (Enzon Inc.) Analogs
Adagen (Enzon Inc.) Brand Names Mixture
- No information avaliable
Adagen (Enzon Inc.) Chemical_Formula
C1821H2834N484O552S14
Adagen (Enzon Inc.) RX_link
http://www.rxlist.com/cgi/generic2/pegademase.htm
Adagen (Enzon Inc.) fda sheet
Adagen (Enzon Inc.) msds (material safety sheet)
Adagen (Enzon Inc.) Synthesis Reference
No information avaliable
Adagen (Enzon Inc.) Molecular Weight
40788.2
Adagen (Enzon Inc.) Melting Point
MacQuarrie R, Buel E. Physical and catalytic properties of the isozymes of adenosine deaminase from human red blood cells.
Adagen (Enzon Inc.) H2O Solubility
No information avaliable
Adagen (Enzon Inc.) State
Liquid
Adagen (Enzon Inc.) LogP
-0.428
Adagen (Enzon Inc.) Dosage Forms
Solution (IM Injection)
Adagen (Enzon Inc.) Indication
For treatment of adenosine deaminase deficiency
Adagen (Enzon Inc.) Pharmacology
Used to replace deficient or inactive adenosine deaminase which leads to severe combined immunodeficiency disease (SCID). The enzyme is responsible for converting adensoine to inosine. In the absence of adenosine deaminase, the purine substrates adenosine, 2'-deoxyadenosine and their metabolites are actually toxic to lymphocytes thereby leading to diminished immune function.
Adagen (Enzon Inc.) Absorption
No information avaliable
Adagen (Enzon Inc.) side effects and Toxicity
No information avaliable
Adagen (Enzon Inc.) Patient Information
No information avaliable
Adagen (Enzon Inc.) Organisms Affected
Humans and other mammals
