Adenosine deaminase
Brand names,
Adenosine deaminase
Analogs
Adenosine deaminase
Brand Names Mixture
Adenosine deaminase
Chemical_Formula
C1821H2834N484O552S14
Adenosine deaminase
RX_link
http://www.rxlist.com/cgi/generic2/pegademase.htm
Adenosine deaminase
fda sheet
Adenosine deaminase
msds (material safety sheet)
Adenosine deaminase
Synthesis Reference
No information avaliable
Adenosine deaminase
Molecular Weight
40788.2
Adenosine deaminase
Melting Point
MacQuarrie R, Buel E. Physical and catalytic properties of the isozymes of adenosine deaminase from human red blood cells.
Adenosine deaminase
H2O Solubility
No information avaliable
Adenosine deaminase
State
Liquid
Adenosine deaminase
LogP
-0.428
Adenosine deaminase
Dosage Forms
Solution (IM Injection)
Adenosine deaminase
Indication
For treatment of adenosine deaminase deficiency
Adenosine deaminase
Pharmacology
Used to replace deficient or inactive adenosine deaminase which leads to severe combined immunodeficiency disease (SCID). The enzyme is responsible for converting adensoine to inosine. In the absence of adenosine deaminase, the purine substrates adenosine, 2'-deoxyadenosine and their metabolites are actually toxic to lymphocytes thereby leading to diminished immune function.
Adenosine deaminase
Absorption
No information avaliable
Adenosine deaminase
side effects and Toxicity
No information avaliable
Adenosine deaminase
Patient Information
No information avaliable
Adenosine deaminase
Organisms Affected
Humans and other mammals