Actimmune (InterMune Inc)
Actimmune (InterMune Inc) Brand names, Actimmune (InterMune Inc) Analogs
Actimmune (InterMune Inc) Brand Names Mixture
- No information avaliable
Actimmune (InterMune Inc) Chemical_Formula
C761H1206N214O225S6
Actimmune (InterMune Inc) RX_link
No information avaliable
Actimmune (InterMune Inc) fda sheet
Actimmune (InterMune Inc) msds (material safety sheet)
Actimmune (InterMune Inc) Synthesis Reference
No information avaliable
Actimmune (InterMune Inc) Molecular Weight
17145.6
Actimmune (InterMune Inc) Melting Point
61 oC (Beldarrain, A. et al., Biochemistry 38:7865-7873 (1999))
Actimmune (InterMune Inc) H2O Solubility
No information avaliable
Actimmune (InterMune Inc) State
Liquid
Actimmune (InterMune Inc) LogP
-0.823
Actimmune (InterMune Inc) Dosage Forms
Solution (subcutaneous Injection)
Actimmune (InterMune Inc) Indication
For treatment of Chronic granulomatous disease, Osteopetrosis
Actimmune (InterMune Inc) Pharmacology
IFN gamma stimulates expression of the immunoglobulin heavy chain C gamma 3 and C gamma 2a germline transcripts in B cells. Many components of the antigen presentation pathways are also up-regulated by interferon gamma. It is also a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of type I interferons. Interferon gamma may also help the body regulate the activity of fibroblasts. By directly blocking the multiplication of fibroblasts and inhibiting the production and action of TGF-b, a potent scar-inducing molecule, Interferon gamma-1b may prevent excessive scarring.
Actimmune (InterMune Inc) Absorption
No information avaliable
Actimmune (InterMune Inc) side effects and Toxicity
No information avaliable
Actimmune (InterMune Inc) Patient Information
No information avaliable
Actimmune (InterMune Inc) Organisms Affected
No information avaliable
