Interferon gamma precursor
Brand names,
Interferon gamma precursor
Analogs
Interferon gamma precursor
Brand Names Mixture
Interferon gamma precursor
Chemical_Formula
C761H1206N214O225S6
Interferon gamma precursor
RX_link
No information avaliable
Interferon gamma precursor
fda sheet
Interferon gamma precursor
msds (material safety sheet)
Interferon gamma precursor
Synthesis Reference
No information avaliable
Interferon gamma precursor
Molecular Weight
17145.6
Interferon gamma precursor
Melting Point
61 oC (Beldarrain, A. et al., Biochemistry 38:7865-7873 (1999))
Interferon gamma precursor
H2O Solubility
No information avaliable
Interferon gamma precursor
State
Liquid
Interferon gamma precursor
LogP
-0.823
Interferon gamma precursor
Dosage Forms
Solution (subcutaneous Injection)
Interferon gamma precursor
Indication
For treatment of Chronic granulomatous disease, Osteopetrosis
Interferon gamma precursor
Pharmacology
IFN gamma stimulates expression of the immunoglobulin heavy chain C gamma 3 and C gamma 2a germline transcripts in B cells. Many components of the antigen presentation pathways are also up-regulated by interferon gamma. It is also a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of type I interferons. Interferon gamma may also help the body regulate the activity of fibroblasts. By directly blocking the multiplication of fibroblasts and inhibiting the production and action of TGF-b, a potent scar-inducing molecule, Interferon gamma-1b may prevent excessive scarring.
Interferon gamma precursor
Absorption
No information avaliable
Interferon gamma precursor
side effects and Toxicity
No information avaliable
Interferon gamma precursor
Patient Information
No information avaliable
Interferon gamma precursor
Organisms Affected
No information avaliable