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Acitretin Brand names, Acitretin Analogs

Acitretin Brand Names Mixture

  • No information avaliable

Acitretin Chemical_Formula


Acitretin RX_link

Acitretin fda sheet

Acitretin FDA

Acitretin msds (material safety sheet)

Acitretin MSDS

Acitretin Synthesis Reference

No information avaliable

Acitretin Molecular Weight

326.429 g/mol

Acitretin Melting Point

228-230 oC

Acitretin H2O Solubility

0.0729 mg/L

Acitretin State


Acitretin LogP


Acitretin Dosage Forms

10 mg and 25 mg gelatin capsules for oral administration

Acitretin Indication

For the treatment of severe psoriasis in adults.

Acitretin Pharmacology

Acitretin is a retinoid. Retinoids have a structure similar to vitamin A and are involved in the normal growth of skin cells. Acitretin works by inhibiting the excessive cell growth and keratinisation (process by which skin cells become thickened due to the deposition of a protein within them) seen in psoriasis. It therefore reduces the thickening of the skin, plaque formation and scaling.

Acitretin Absorption

Oral absorption of acitretin is optimal when given with food, and is linear and proportional with increasing doses from 25 to 100 mg. Approximately 72% (range 47% to 109%) of the administered dose was absorbed after a single 50 mg dose of acitretin was given to 12 healthy subjects.

Acitretin side effects and Toxicity

Oral, rat: LD50 = >4000 mg/kg. Symptoms of overdose include headache and vertigo.

Acitretin Patient Information

Acitretin Organisms Affected

Humans and other mammals