Abciximab
Abciximab Brand names, Abciximab Analogs
Abciximab Brand Names Mixture
- No information avaliable
Abciximab Chemical_Formula
C6462H9964N1690O2049S48
Abciximab RX_link
http://www.rxlist.com/cgi/generic2/abcixim.htm
Abciximab fda sheet
Abciximab msds (material safety sheet)
Abciximab Synthesis Reference
(sequence listed in Kohmura C, Gold HK, Yasuda T, Holt R, Nedelman MA, Guerrero JL, Weisman HF, Collen D. A chimeric murine/human antibody Fab fragment directed against the platelet GPIIb/IIIa receptor enhances and sustains arterial thrombolysis with recombinant tissue-type plasminogen activator in baboons.Arterioscler Thromb. 1993 Dec;13(12):1837-42.) patent EP418316
Abciximab Molecular Weight
145651.1
Abciximab Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Abciximab H2O Solubility
No information avaliable
Abciximab State
Liquid
Abciximab LogP
-0.424
Abciximab Dosage Forms
Solution (IV Infusion)
Abciximab Indication
For treatment of myocardial infarction, adjunct to percutaneous coronory intervention, unstable angina
Abciximab Pharmacology
Used for the treatment of myocardial infarction and the prevention of platelet aggregation. Abciximab inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules to GPIIb/IIIa receptor sites on activated platelets.
Abciximab Absorption
No information avaliable
Abciximab side effects and Toxicity
No information avaliable
Abciximab Patient Information
No information avaliable
Abciximab Organisms Affected
Humans and other mammals
