7E3 antibody
7E3 antibody Brand names, 7E3 antibody Analogs
7E3 antibody Brand Names Mixture
- No information avaliable
7E3 antibody Chemical_Formula
C6462H9964N1690O2049S48
7E3 antibody RX_link
http://www.rxlist.com/cgi/generic2/abcixim.htm
7E3 antibody fda sheet
7E3 antibody msds (material safety sheet)
7E3 antibody Synthesis Reference
(sequence listed in Kohmura C, Gold HK, Yasuda T, Holt R, Nedelman MA, Guerrero JL, Weisman HF, Collen D. A chimeric murine/human antibody Fab fragment directed against the platelet GPIIb/IIIa receptor enhances and sustains arterial thrombolysis with recombinant tissue-type plasminogen activator in baboons.Arterioscler Thromb. 1993 Dec;13(12):1837-42.) patent EP418316
7E3 antibody Molecular Weight
145651.1
7E3 antibody Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
7E3 antibody H2O Solubility
No information avaliable
7E3 antibody State
Liquid
7E3 antibody LogP
-0.424
7E3 antibody Dosage Forms
Solution (IV Infusion)
7E3 antibody Indication
For treatment of myocardial infarction, adjunct to percutaneous coronory intervention, unstable angina
7E3 antibody Pharmacology
Used for the treatment of myocardial infarction and the prevention of platelet aggregation. Abciximab inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules to GPIIb/IIIa receptor sites on activated platelets.
7E3 antibody Absorption
No information avaliable
7E3 antibody side effects and Toxicity
No information avaliable
7E3 antibody Patient Information
No information avaliable
7E3 antibody Organisms Affected
Humans and other mammals
