2-Norbornanamine, N,2,3,3-tetramethyl-
Brand names,
2-Norbornanamine, N,2,3,3-tetramethyl-
Analogs
- 2-Methylamino-2,3,3-trimethylnorbornane
- 2-Methylaminoisocamphane
- 2-Norbornanamine, N,2,3,3-tetramethyl-
- 2-Norbornanamine, N,2,3,3-tetramethyl-, hydrochloride
- 3-Methylaminoisocamphane
- 3-Methylaminoisocamphane hydrochloride
- Inversine
- Inversine hydrochloride
- Mecamilamina
- Mecamine
- Mecamine hydrochloride
- Mecamylamine Hydrochloride
- Mekamin hydrochloride
- Mekamine
- Mevasin hydrochloride
- Mevasine
- Revertina
- Versamine
2-Norbornanamine, N,2,3,3-tetramethyl-
Brand Names Mixture
2-Norbornanamine, N,2,3,3-tetramethyl-
Chemical_Formula
C11H21N
2-Norbornanamine, N,2,3,3-tetramethyl-
RX_link
http://www.rxlist.com/cgi/generic2/mecamylamine.htm
2-Norbornanamine, N,2,3,3-tetramethyl-
fda sheet
2-Norbornanamine, N,2,3,3-tetramethyl-
msds (material safety sheet)
2-Norbornanamine, N,2,3,3-tetramethyl-
Synthesis Reference
No information avaliable
2-Norbornanamine, N,2,3,3-tetramethyl-
Molecular Weight
167.291 g/mol
2-Norbornanamine, N,2,3,3-tetramethyl-
Melting Point
<25 oC
2-Norbornanamine, N,2,3,3-tetramethyl-
H2O Solubility
No information avaliable
2-Norbornanamine, N,2,3,3-tetramethyl-
State
Liquid
2-Norbornanamine, N,2,3,3-tetramethyl-
LogP
2.477
2-Norbornanamine, N,2,3,3-tetramethyl-
Dosage Forms
Tablets
2-Norbornanamine, N,2,3,3-tetramethyl-
Indication
For the treatment of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension
2-Norbornanamine, N,2,3,3-tetramethyl-
Pharmacology
Mecamylamine is a potent, oral antihypertensive agent and ganglion blocker, and is a secondary amine. Mecamylamine is indicated for the management of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension. Mecamylamine reduces blood pressure in both normotensive and hypertensive individuals. A small oral dosage often produces a smooth and predictable reduction of blood pressure. Although this antihypertensive effect is predominantly orthostatic, the supine blood pressure is also significantly reduced. Mecamylamine crosses the blood-brain and placental barriers.
2-Norbornanamine, N,2,3,3-tetramethyl-
Absorption
Mecamylamine is almost completely absorbed from the gastrointestinal tract
2-Norbornanamine, N,2,3,3-tetramethyl-
side effects and Toxicity
No information avaliable
2-Norbornanamine, N,2,3,3-tetramethyl-
Patient Information
APRD00458_PI.txt
2-Norbornanamine, N,2,3,3-tetramethyl-
Organisms Affected
Humans and other mammals