Triglide

Triglide Brand names, Triglide Analogs

Triglide Brand Names Mixture

No information avaliable

Triglide Chemical_Formula

C₂₀H₂₁ClO₄

Triglide RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

Triglide fda sheet

Triglide FDA

Triglide msds (material safety sheet)

Triglide MSDS

Triglide Synthesis Reference

No information avaliable

Triglide Molecular Weight

360.831 g/mol

Triglide Melting Point

80.5 °C

Triglide H₂O Solubility

0.25mg/ml at 25 °C

Triglide State

Solid

Triglide LogP

5.575

Triglide Dosage Forms

Capsule; Tablet

Triglide Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Triglide Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

Triglide Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Triglide side effects and Toxicity

LD₅₀=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Triglide Patient Information