Finofibrate en es it fr

Finofibrate Brand names, Finofibrate Analogs

Finofibrate Brand Names Mixture

  • No information avaliable

Finofibrate Chemical_Formula

C20H21ClO4

Finofibrate RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

Finofibrate fda sheet

Finofibrate FDA

Finofibrate msds (material safety sheet)

Finofibrate MSDS

Finofibrate Synthesis Reference

No information avaliable

Finofibrate Molecular Weight

360.831 g/mol

Finofibrate Melting Point

80.5 °C

Finofibrate H2O Solubility

0.25mg/ml at 25 °C

Finofibrate State

Solid

Finofibrate LogP

5.575

Finofibrate Dosage Forms

Capsule; Tablet

Finofibrate Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Finofibrate Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

Finofibrate Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Finofibrate side effects and Toxicity

LD50=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Finofibrate Patient Information

No information avaliable

Finofibrate Organisms Affected

Humans and other mammals