Baci-rx

• Anti-Bacterial Agents
• Anti-Infective Agents, Local
• ATC:D06AX05
• ATC:R02AB04

• Baci-rx
• Baciguent
• Baciim
• Bacitracin Bacillus licheniformis
• Ziba-rx

• No information avaliable

C₆₆H₁₀₃N₁₇O₁₆S

http://www.rxlist.com/cgi/generic3/bacit.htm

Baci-rx MSDS

No information avaliable

1422.69 g/mol

221 - 225 ^oC

Freely soluble

Solid

-1.025

Drug premix; Ointment; Powder; Powder for solution

For the treatment of infants with pneumonia and empyema caused by staphylococci shown to be susceptible to the drug. Also used in ointment form for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections.

Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. As a polypeptide, toxic, and difficult to use chemical, Bacitracin doesn't work well orally, however is very effective topically. Bacitracin exerts pronounced antibacterial action in vitro against a variety of gram-positive and a few gram-negative organisms. However, among systemic diseases, only staphylococcal infections qualify for consideration of bacitracin therapy.

Absorption of bacitracin following intramuscular injection is rapid and complete. Absorption from the gastrointestinal tract following oral administration is not appreciable. Absorption following topical application is negligible.

Oral, mouse: LD₅₀ = >3750 mg/kg.

Enteric bacteria and other eubacteria