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Baciguent Brand names, Baciguent Analogs

Baciguent Brand Names Mixture

  • No information avaliable

Baciguent Chemical_Formula

C66H103N17O16S

Baciguent RX_link

http://www.rxlist.com/cgi/generic3/bacit.htm

Baciguent fda sheet

Baciguent msds (material safety sheet)

Baciguent MSDS

Baciguent Synthesis Reference

No information avaliable

Baciguent Molecular Weight

1422.69 g/mol

Baciguent Melting Point

221 - 225 oC

Baciguent H2O Solubility

Freely soluble

Baciguent State

Solid

Baciguent LogP

-1.025

Baciguent Dosage Forms

Drug premix; Ointment; Powder; Powder for solution

Baciguent Indication

For the treatment of infants with pneumonia and empyema caused by staphylococci shown to be susceptible to the drug. Also used in ointment form for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections.

Baciguent Pharmacology

Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. As a polypeptide, toxic, and difficult to use chemical, Bacitracin doesn't work well orally, however is very effective topically. Bacitracin exerts pronounced antibacterial action in vitro against a variety of gram-positive and a few gram-negative organisms. However, among systemic diseases, only staphylococcal infections qualify for consideration of bacitracin therapy.

Baciguent Absorption

Absorption of bacitracin following intramuscular injection is rapid and complete. Absorption from the gastrointestinal tract following oral administration is not appreciable. Absorption following topical application is negligible.

Baciguent side effects and Toxicity

Oral, mouse: LD50 = >3750 mg/kg.

Baciguent Patient Information

Baciguent Organisms Affected

Enteric bacteria and other eubacteria