Bacitracin Bacillus licheniformis
Bacitracin Bacillus licheniformis Brand names, Bacitracin Bacillus licheniformis Analogs
Bacitracin Bacillus licheniformis Brand Names Mixture
- No information avaliable
Bacitracin Bacillus licheniformis Chemical_Formula
C66H103N17O16S
Bacitracin Bacillus licheniformis RX_link
http://www.rxlist.com/cgi/generic3/bacit.htm
Bacitracin Bacillus licheniformis fda sheet
Bacitracin Bacillus licheniformis msds (material safety sheet)
Bacitracin Bacillus licheniformis Synthesis Reference
No information avaliable
Bacitracin Bacillus licheniformis Molecular Weight
1422.69 g/mol
Bacitracin Bacillus licheniformis Melting Point
221 - 225 oC
Bacitracin Bacillus licheniformis H2O Solubility
Freely soluble
Bacitracin Bacillus licheniformis State
Solid
Bacitracin Bacillus licheniformis LogP
-1.025
Bacitracin Bacillus licheniformis Dosage Forms
Drug premix; Ointment; Powder; Powder for solution
Bacitracin Bacillus licheniformis Indication
For the treatment of infants with pneumonia and empyema caused by staphylococci shown to be susceptible to the drug. Also used in ointment form for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections.
Bacitracin Bacillus licheniformis Pharmacology
Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. As a polypeptide, toxic, and difficult to use chemical, Bacitracin doesn't work well orally, however is very effective topically. Bacitracin exerts pronounced antibacterial action in vitro against a variety of gram-positive and a few gram-negative organisms. However, among systemic diseases, only staphylococcal infections qualify for consideration of bacitracin therapy.
Bacitracin Bacillus licheniformis Absorption
Absorption of bacitracin following intramuscular injection is rapid and complete. Absorption from the gastrointestinal tract following oral administration is not appreciable. Absorption following topical application is negligible.
Bacitracin Bacillus licheniformis side effects and Toxicity
Oral, mouse: LD50 = >3750 mg/kg.
Bacitracin Bacillus licheniformis Patient Information
Bacitracin Bacillus licheniformis Organisms Affected
Enteric bacteria and other eubacteria
