Categoria
Procyklidin
Marchi,
Procyklidin
Analoghi
Procyklidin
Marchi miscela
No information avaliable
Procyklidin
Formula chimica
C19H29NO
Procyklidin
RX link
No information avaliable
Procyklidin
FDA foglio
Procyklidin
DMS (foglio di materiale di sicurezza)
Procyklidin
Sintesi di riferimento
Adamson, US Pat. 2.891.890 (1959 a Burroughs Wellcome)
Procyklidin
Peso molecolare
287.44 g/mol
Procyklidin
Temperatura di fusione
86 oC
Procyklidin
H2O Solubilita
Moderatamente solubile in acqua, ~ 30 mg / ml
Procyklidin
Stato
Solid
Procyklidin
LogP
4.37
Procyklidin
Forme di dosaggio
Tablet; Elixir
Procyklidin
Indicazione
Per il trattamento della malattia di Parkinson (soprattutto indotto da farmaci)
Procyklidin
Farmacologia
Procyclidine ha un atropina-come azione. I suoi effetti antispasmodico si pensa siano correlati al blocco del centro di recettori colinergici M1, M2 e M4. E 'utilizzato per il trattamento sintomatico parkinsonismo e disfunzione extrapiramidale causata da farmaci antipsicotici.
Procyklidin
Assorbimento
Nessuna informazione disponibile
Procyklidin
Tossicita
LD50 = 60 mg / kg (IV nei topi)
Procyklidin
Informazioni paziente
Patient Information:
Follow your doctors instructions for taking this medicine. This medicine can be taken with food or a snack,
to minimize stomach upset. As your body becomes used to the medicine, it should be taken on an empty
stomach. Talk to your doctor about the best time of day to take the medicine. For patients taking the
extended-release forms, swallow the tablet whole, do NOT CRUSH or CHEW. You may break the tablet in half
if the whole pill is too large for you to take.
This medicine can cause dizziness or drowsiness. Be cautious when driving or performing other hazardous
activities. This medicine can impair judgment. Do NOT increase your dose of this medicine without first
talking to your doctor, even if you feel that the medicine is not working.
Discuss the risks and benefits of using this medicine during pregnancy. It is unknown whether this medicine
is excreted in breast milk. DO NOT breastfeed while taking this medicine until you have talked to your
doctor or pediatrician.
Procyklidin
Atto interessato organismi
Gli esseri umani e altri mammiferi