Categoria
NOV
Marchi,
NOV
Analoghi
NOV
Marchi miscela
Alka Seltzer Plus Cold Medicine Evt (Acetylsalicylic Acid + Chlorpheniramine Maleate + Phenylpropanolamine Bitartrate) Alka-Seltzer Plus Cold Medicine - Evt (Acetylsalicylic Acid + Chlorpheniramine Maleate + Phenylpropanolamine Bitartrate) Allergy Sinus Medication - Caplet (Acetaminophen + Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Ana-Kit (2mg/Tab Orl, 1mg/Ml Liq Sc Im) (Chlorpheniramine Maleate + Epinephrine) Ana-Kit (Chlorpheniramine Maleate + Epinephrine Hcl) Anakit Insect Sting Treatment Kit (Chlorpheniramine Maleate + Epinephrine) Bronchodex D Cap (Chlorpheniramine Maleate + Pheniramine Maleate + Phenylpropanolamine Hydrochloride) Children's Tylenol Cold Chewable Tablets (Acetaminophen + Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Children's Tylenol Cold Liquid (Acetaminophen + Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Children's Tylenol Cold Liquid with Dm (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Chlor Tripolon Decongest Syr (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Cold Decongestant Long Acting Cap (Chlorpheniramine Maleate + Pheniramine Maleate + Phenylpropanolamine Hydrochloride) Coltalin Tablet (Acetaminophen + Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Contac Cold Capsules (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Contac Cold Extra Strength Capsules (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Contac Cough Cold and Flu Caplets (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Phenylpropanolamine Hydrochloride) Contact C Src (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Coricidin D Long Acting Tab (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Coricidin D Tab (Acetylsalicylic Acid + Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Coricidin Sinus Headache Tab (Acetaminophen + Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Coricidin Tab (Acetylsalicylic Acid + Chlorpheniramine Maleate) Corsym Suspension (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Counteract Sinus and Allergy (Acetaminophen + Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Dristan Capsules (Acetylsalicylic Acid + Caffeine + Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Extra Strength Allergy Plus Sinus Relief (Acetaminophen + Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Extra Strength Allergy Sinus Medication (Acetaminophen + Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Extra Strength Contac C - Src (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Extra Strength Nighttime Cold Relief-Caplet (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Extra Strength Tylenol Cold and Flu Powder (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Extra Strength Tylenol Cold Nighttime Caplet (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Extra Strength Tylenol Sinus Nighttime (Acetaminophen + Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Grippalin & C Tab (Acetaminophen + Chlorpheniramine Maleate + Vitamin C) Neocitran Total (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Omni-Tuss Sus (Chlorpheniramine + Codeine + Ephedrine As Resin Complex + Guaiacol Carbonate + Phenyltoloxamine) Once-a-Day Benylin Cold Cap (Chlorpheniramine Maleate + Pseudoephedrine Hydrochloride) Ornade Af Liquid (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Ornade Af Spansule Src (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Ornade Dm 10 Liq (Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Phenylpropanolamine Hydrochloride) Ornade Dm 15 Liq (Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Phenylpropanolamine Hydrochloride) Ornade Dm 30 Liq (Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Phenylpropanolamine Hydrochloride) Ornade Expectorant Cough Formula (Chlorpheniramine Maleate + Guaifenesin + Phenylpropanolamine Hydrochloride) Ornade Liquid (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Ornade Spansule Src (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Pendamine (Chlorpheniramine Maleate + Dexamethasone + Dihydrostreptomycin Sulfate + Penicillin G Procaine) Pentuss Srs (Chlorpheniramine Maleate + Codeine) Reg.Str.Cold Medic.(Night Time Relief)Caplet (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Regular Strength Tylenol Cold and Flu Powder (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Regular Strength Tylenol Cold Nighttime Caplet (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Sine-Off Allergy Tab (Acetaminophen + Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Theraflu Flu Cold and Cough Medicine (Acetaminophen + Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride) Tri-Anamine Cold Syrup (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Triaminic Cold and Allergy Syrup (Chlorpheniramine Maleate + Phenylpropanolamine Hydrochloride) Triaminic Dm Expectorant Syr (Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Guaifenesin + Pseudoephedrine Hydrochloride) Triaminic Expectorant Syr (Chlorpheniramine Maleate + Guaifenesin + Pseudoephedrine Hydrochloride) Triaminicol Dm Syrup (Chlorpheniramine Maleate + Dextromethorphan Hydrobromide + Pseudoephedrine Hydrochloride)
NOV
Formula chimica
C16H19ClN2
NOV
RX link
http://www.rxlist.com/cgi/generic3/chlorpheniramine.htm
NOV
FDA foglio
NOV
DMS (foglio di materiale di sicurezza)
NOV
Sintesi di riferimento
Nessuna informazione disponibile
NOV
Peso molecolare
274.788 g/mol
NOV
Temperatura di fusione
142 oC (boiling point)
NOV
H2O Solubilita
5,5 g / L
NOV
Stato
Liquid
NOV
LogP
3.563
NOV
Forme di dosaggio
Liquidi; Sciroppo; Tablet; Tablet (a rilascio prolungato)
NOV
Indicazione
Per il trattamento della rinite, orticaria, allergie, raffreddore, asma e febbre da fieno.
NOV
Farmacologia
Nelle reazioni allergiche un allergene interagisce con e cross-links superficie anticorpi IgE sui mastociti e dei basofili. Una volta che i mastociti antigene-anticorpo complesso è formato, una complessa serie di eventi si verifica che alla fine conduce alla cella-degranulazione e il rilascio di istamina (e di altri mediatori chimici) da mastociti e dei basofili. Una volta rilasciato, istamina può reagire con i tessuti locali o diffuse attraverso i recettori dell'istamina. Istamina, che delibera su H1-recettori, produce prurito, vasodilatazione, ipotensione, vampate, cefalea, tachicardia, e broncocostrizione. Istamina aumenta anche vascolare permeabilità e potenzia il dolore. Clorfeniramina, è un antagonista H1 dell'istamina (o più correttamente, un agonista istamina inverso) della classe alchilammina. Compete con l'istamina per il normale H1- siti recettori sulle cellule effettrici del tratto gastrointestinale, vasi sanguigni e del tratto respiratorio. Essa fornisce efficaci, temporaneo sollievo di starnuti, lacrimazione e prurito e naso che cola a causa di fieno febbre e delle allergie respiratorie.
NOV
Assorbimento
Ben assorbito nel tratto gastrointestinale.
NOV
Tossicita
LD50 = 306 mg / kg per l'uomo, mite tossina riproduttiva per le donne in età fertile.
NOV
Informazioni paziente
May cause excitability especially in children. Do not take this
product unless directed by a physician, if you have a breathing problem such as emphysema or chronic bronchitis, or
if you have glaucoma or difficulty in urination due to enlargement of the prostate gland. May cause drowsiness;
alcohol, sedatives and tranquilizers may increase the drowsiness effect. Avoid alcoholic beverages, and do not take
this product if you are taking sedatives or tranquilizers without first consulting your physician. Use caution when
driving a motor vehicle or operating machinery.
NOV
Atto interessato organismi
Gli esseri umani e altri mammiferi
