Gentab
Categoria
Gentab Marchi, Gentab Analoghi
Gentab Marchi miscela
Gentab Formula chimica
C9H13NO
Gentab RX link
No information avaliable
Gentab FDA foglio
Gentab DMS (foglio di materiale di sicurezza)
Gentab Sintesi di riferimento
Vanderbitle, Hass, Ind. Eng.. Chem. 32, 34 (1940)
Gentab Peso molecolare
151.206 g/mol
Gentab Temperatura di fusione
190-194 oC
Gentab H2O Solubilita
Solubile
Gentab Stato
Solid
Gentab LogP
0.974
Gentab Forme di dosaggio
Compressa, iniezione; Sciroppo
Gentab Indicazione
Per il trattamento della congestione nasale, il controllo dell'incontinenza urinaria, priapismo e obesità.
Gentab Farmacologia
Fenilpropanolamina (PPA), un agente simpaticomimetico strutturalmente simile alla pseudoefedrina, è usato per curare la congestione nasale. Fenilpropanolamina si trova in formulazioni soppressore dell'appetito e con guaifenesinin nella tosse-raffreddore formulazioni. Nel 2000, la FDA ha chiesto che tutte le aziende farmaceutiche interrompere la commercializzazione di prodotti contenenti fenilpropanolamina, a causa di un aumentato rischio di ictus emorragico in donne che hanno utilizzato fenilpropanolamina.
Gentab Assorbimento
Ridotta biodisponibilità (circa 38%) dal tratto gastrointestinale a causa del metabolismo di primo passaggio da monoamino-ossidasi nello stomaco e fegato.
Gentab Tossicita
Può indurre extrasistoli ventricolari e brevi parossismi di tachicardia ventricolare, una sensazione di pienezza nella testa e formicolio alle estremità; LD50 = 1490mg/kg (per via orale nel ratto)
Gentab Informazioni paziente
PATIENT INFORMATION
Description
--------------------------------------------------------------------------------
This medicine is used to treat nasal congestion caused by colds or hay fever. Your doctor may prescribe this medicine for
other conditions as well.
General Information
--------------------------------------------------------------------------------
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in
this database. If you have questions about your medicines, talk to your healthcare provider.
Proper use of this medicine
--------------------------------------------------------------------------------
For proper use of this medicine, follow the directions on the package, unless otherwise instructed by your doctor. To use
a nose spray: gently blow your nose. Then sit back and tilt your head back slightly. Place the tip of the spray container
into the nose. Close off the other nostril with your other hand. Spray into the nose. Wait at least one minute in between
sprays. After using, rinse the tip of the sprayer in hot water and dry. This prevents contamination.
Missed Dose
--------------------------------------------------------------------------------
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your
regular schedule. Do not double doses.
Storage
--------------------------------------------------------------------------------
Follow package directions for proper storage. Keep away from heat, moisture or light.
Possible Side Effects
--------------------------------------------------------------------------------
Some common side effects reported with this medicine include:
stinging
burning
sneezing
increase in nasal discharge
If you experience other bothersome side effects, talk to your health care provider.
Some common side effects with this medicine include:
burning or stinging inside your nose
confusion
nervousness
headache
nausea
vomiting
Report any of the following to your doctor:
dizziness
or fainting spells
difficulty breathing
chest pain
rapid heart beat
increased sweating
tingling or numbness in the hands or feet
Warnings/Precautions
--------------------------------------------------------------------------------
Do NOT use more that the recommended dose of this medicine.
Do NOT use more of this medicine or longer than prescribed.
Using this medicine longer that 3-5 days can cause a condition known as "rebound congestion".
Overdose
--------------------------------------------------------------------------------
Seek medical attention immediately. For non emergencies, contact your local or regional poison control center
Drug Interactions
--------------------------------------------------------------------------------
This medicine can cause in increase in toxic effects to the heart when taken with other stimulants. Avoid taking with:
theophylline
digoxin
general anesthetics
atropine
MAO inhibitors.
Taking this medicine with the following herbs can cause increased side effects including high blood pressure and should be
avoided:
ephedra
yohimbe
This medicine can interact with the following drugs:
atropine
bromocriptine
diuretics (water pills)
linezolid
maprotiline
drugs used for depression
high blood pressure medications
drugs used for migraine headaches
oxytocin
vasopressin
For more information on specific drug interactions, talk to your doctor or pharmacist.
Pregnancy/Nursing
--------------------------------------------------------------------------------
Talk to your doctor about using this medicine during pregnancy or nursing to discuss any possible risks to you or your baby.
More Information
--------------------------------------------------------------------------------
For more information about this medicine, talk to your healthcare provider.
Description
--------------------------------------------------------------------------------
This medicine is used to treat nasal congestion caused by colds or hay fever. Your doctor may prescribe this medicine for
other conditions as well.
General Information
--------------------------------------------------------------------------------
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in
this database. If you have questions about your medicines, talk to your healthcare provider.
Proper use of this medicine
--------------------------------------------------------------------------------
For proper use of this medicine, follow the directions on the package, unless otherwise instructed by your doctor. To use
a nose spray: gently blow your nose. Then sit back and tilt your head back slightly. Place the tip of the spray container
into the nose. Close off the other nostril with your other hand. Spray into the nose. Wait at least one minute in between
sprays. After using, rinse the tip of the sprayer in hot water and dry. This prevents contamination.
Missed Dose
--------------------------------------------------------------------------------
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your
regular schedule. Do not double doses.
Storage
--------------------------------------------------------------------------------
Follow package directions for proper storage. Keep away from heat, moisture or light.
Possible Side Effects
--------------------------------------------------------------------------------
Some common side effects reported with this medicine include:
stinging
burning
sneezing
increase in nasal discharge
If you experience other bothersome side effects, talk to your health care provider.
Some common side effects with this medicine include:
burning or stinging inside your nose
confusion
nervousness
headache
nausea
vomiting
Report any of the following to your doctor:
dizziness
or fainting spells
difficulty breathing
chest pain
rapid heart beat
increased sweating
tingling or numbness in the hands or feet
Warnings/Precautions
--------------------------------------------------------------------------------
Do NOT use more that the recommended dose of this medicine.
Do NOT use more of this medicine or longer than prescribed.
Using this medicine longer that 3-5 days can cause a condition known as "rebound congestion".
Overdose
--------------------------------------------------------------------------------
Seek medical attention immediately. For non emergencies, contact your local or regional poison control center
Drug Interactions
--------------------------------------------------------------------------------
This medicine can cause in increase in toxic effects to the heart when taken with other stimulants. Avoid taking with:
theophylline
digoxin
general anesthetics
atropine
MAO inhibitors.
Taking this medicine with the following herbs can cause increased side effects including high blood pressure and should be
avoided:
ephedra
yohimbe
This medicine can interact with the following drugs:
atropine
bromocriptine
diuretics (water pills)
linezolid
maprotiline
drugs used for depression
high blood pressure medications
drugs used for migraine headaches
oxytocin
vasopressin
For more information on specific drug interactions, talk to your doctor or pharmacist.
Pregnancy/Nursing
--------------------------------------------------------------------------------
Talk to your doctor about using this medicine during pregnancy or nursing to discuss any possible risks to you or your baby.
More Information
--------------------------------------------------------------------------------
For more information about this medicine, talk to your healthcare provider.
Gentab Atto interessato organismi
Gli esseri umani e altri mammiferi
