Categoria
Dantrium Intravenous
Marchi,
Dantrium Intravenous
Analoghi
Dantrium Intravenous
Marchi miscela
Acti Poultice (Eucalyptus Oil + Magnesium Sulfate + Menthol + Methyl Salicylate + Thymol) Agobyl Granule (Magnesium Sulfate + Peptone) Agobyl Liquide (Magnesium Sulfate + Peptone) Alsilax (Boldo + Cascara Sagrada + Magnesium Sulfate + Pancreatin + Peptone) Amino Acid Concentrate Inj (Arginine Hcl + Calcium Chloride + Dexpanthenol + Dextrose + Dl-Methionine + Glutamic Acid + Histidine Hcl + Isoleucine + L-Cysteine Hydrochloride + L-Lysine Hydrochloride + Leucine + Magnesium Sulfate + Nicotinamide + Phenylalanine + Potassium Chloride + Sodium Acetate + Threonine + Tryptophan + Valine + Vitamin B1 (Thiamine) + Vitamin B12 + Vitamin B2 (Riboflavin) + Vitamin B6 (Pyridoxine)) Amino Acid Formula Inj (Alanine + Arginine + Calcium Chloride + Calcium D-Pantothenate + Dextrose + Dl-Methionine + Glutamic Acid + Glycine + Histidine + Isoleucine + L-Aspartic Acid + Leucine + Lysine + Magnesium Sulfate + Nicotinamide + Phenylalanine + Potassium Chloride + Proline + Pyridoxine Hydrochloride + Riboflavin 5'-Phosphate Sodium + Serine + Sodium Acetate + Sodium Glutamate + Thiamine Hydrochloride + Threonine + Tryptophan + Tyrosine + Valine + Vitamin B12) Amino Acid Formula Inj (Alanine + Arginine + Calcium Chloride + Calcium D-Pantothenate + Dextrose + Glutamic Acid + Glycine + Histidine + Isoleucine + L-Aspartic Acid + Leucine + Lysine + Magnesium Sulfate + Methionine + Nicotinamide + Phenylalanine + Potassium Chloride + Proline + Pyridoxine Hydrochloride + Riboflavin-5-Phosphate + Serine + Sodium Acetate + Sodium Glutamate + Thiamine Hydrochloride + Threonine + Tryptophan + Tyrosine + Valine + Vitamin B12) Amino Acid Inj (Arginine + Calcium Chloride + D-Pantothenic Acid (Calcium D-Pantothenate) + Dextrose + Histidine + Isoleucine + L-Cysteine Hydrochloride + Leucine + Lysine + Magnesium Sulfate + Methionine + Nicotinamide + Phenylalanine + Potassium Chloride + Pyridoxine Hydrochloride + Sodium Acetate + Threonine + Tryptophan + Valine + Vitamin B1 + Vitamin B12 + Vitamin B2) Amino Lite (Arginine + Calcium Chloride + Dextrose + Isoleucine + L-Cysteine Hydrochloride + L-Histidine Hcl + L-Lysine Hydrochloride + Leucine + Magnesium Sulfate + Methionine + Nicotinic Acid + Phenylalanine + Potassium Chloride + Pyridoxine Hydrochloride + Sodium Glutamate + Thiamine Hydrochloride + Threonine + Tryptophan + Valine + Vitamin B12 + Vitamin B2 (Riboflavin 5'-Phosphate Sodium)) Amino Solution - Liq (Calcium Chloride + Calcium D-Pantothenate + Casein Hydrolysate + Dextrose + Magnesium Sulfate + Nicotinamide + Pyridoxine Hydrochloride + Sodium Acetate + Vitamin B1 (Acetiamine) + Vitamin B12 + Vitamin B2) Amino Solution Inj (Arginine + Calcium Chloride + Calcium D-Pantothenate + Dextrose + Dl-Methionine + Histidine + Isoleucine + Leucine + Lysine + Magnesium Sulfate + Nicotinamide + Phenylalanine + Sodium Acetate + Threonine + Tryptophan + Valine + Vitamin B1 + Vitamin B12 + Vitamin B2 + Vitamin B6) Anticoryzax (Calcium Lactophosphate + Magnesium Sulfate + Ribonucleic Acid + Vitamin C) Bvs Amino Acid Solution Inj (Arginine Hcl + Calcium Chloride + Dexpanthenol + Dextrose + Dl-Isoleucine + L-Cysteine Hydrochloride + L-Histidine Hcl + L-Lysine Hydrochloride + Leucine + Magnesium Sulfate + Methionine + Nicotinamide + Phenylalanine + Potassium Chloride + Pyridoxine Hydrochloride + Sodium Acetate Hemodialysis + Sodium Glutamate + Threonine + Tryptophan + Valine + Vitamin B1 + Vitamin B12 + Vitamin B2) Bylium Liq (Boldo + Cascara Sagrada + Magnesium Sulfate + Pancreatin + Peptone) Calcium Lactate Et Magnesium Sulfate (Calcium Lactate + Magnesium Sulfate) Calcium/Magnesium Drink (Calcium (Calcium Lactate, Calcium Carbonate, Calcium Glycerophosphate) + Magnesium (Magnesium Citrate, Magnesium Sulfate, Magnesium Oxide)) Calf Electrolytes (Calcium Lactate + Ferrous Sulfate + Magnesium Sulfate + Potassium Chloride + Sodium Chloride + Vitamin a + Vitamin B12) Calf-Lyte (Calcium Chloride + Calcium D-Pantothenate + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Potassium Citrate + Potassium Phosphate Monobasic + Sodium Chloride + Sodium Phosphate Monobasic + Vitamin C) Disc-Discovery Tablets (Calcium (Calcium Phosphate (Dibasic), Calcium Ascorbate) + Magnesium (Magnesium Sulfate, Magnesium Oxide) + Manganese (Manganese Sulfate) + Potassium (Potassium Citrate) + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C (Ascorbic Acid, Calcium Ascorbate) + Vitamin D3 (Cholecalciferol) + Zinc Sulfate) Eau Purgative Riga (Magnesium Sulfate + Sodium Sulfate) Electrosul (Calcium Chloride + Calcium D-Pantothenate + Cobalt Sulfate + Copper Sulfate + Ferrous Sulfate + Magnesium Sulfate + Manganese Sulfate + Nicotinic Acid + Potassium Chloride + Sodium Chloride + Sulfamerazine Sodium + Sulfathiazole Sodium + Vitamin a + Vitamin B12 + Vitamin B2 + Vitamin D3 + Zinc Sulfate) Flex Capsules (Calcium (Calcium Ascorbate) + Magnesium Sulfate + Potassium (Potassium Sulfate)) Formule 1705 - Liq (Magnesium Sulfate + Ox Bile Extract) Ion Aid (Calcium Gluconate + Dextrose + Glycine + Magnesium Sulfate + Potassium Phosphate Monobasic + Sodium Chloride) Laxabyl No109 (Barberry Root + Boldo + Cascara Sagrada + Magnesium Sulfate + Pancreatin + Peptone + Taraxacum Officinale Weber) Life Guard H E Pws (Calcium Phosphate (Dibasic) + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Sodium Bicarbonate + Sodium Chloride) Life Guard Oral (Calcium Phosphate (Dibasic) + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Protein + Sodium Bicarbonate + Sodium Chloride) Life Guard Pws Twin-Pak (Calcium Phosphate + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Protein + Sodium Bicarbonate + Sodium Chloride) Life-Guard H.E. Pwr (Calcium Phosphate + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Sodium Bicarbonate + Sodium Chloride) Magnesium Cap (Magnesium Oxide + Magnesium Sulfate) Magnesium Sulfate in 5%Dextrose Inj(20mg/Ml) (Dextrose + Magnesium Sulfate) Medi-3-Sulvita (Calcium Chloride + D-Pantothenic Acid + Magnesium Sulfate + Nicotinamide + Potassium Chloride + Sodium Acetate + Sodium Chloride + Sulfamerazine Sodium + Sulfamethazine Sodium + Sulfathiazole Sodium + Vitamin a + Vitamin B12 + Vitamin B2 + Vitamin D3) Multi-Vi-Min Capsules (Biotin + Chromium (Chromium Hvp Chelate) + D-Pantothenic Acid (Calcium D-Pantothenate) + Folic Acid + Iron (Ferric Ammonium Citrate) + Magnesium Sulfate + Manganese (Manganese Oxide) + Molybdenum (Sodium Molybdate) + Nicotinamide + Potassium (Potassium Chloride) + Selenium (Sodium Selenite) + Vitamin a (Vitamin a Palmitate) + Vitamin B1 (Thiamine Hydrochloride) + Vitamin B12 + Vitamin B2 (Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxal-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C + Vitamin E (Dl-Alpha Tocopheryl Acetate) + Zinc Sulfate) Multiple Electrolyte Additive Inj (Calcium Gluconate + Magnesium Sulfate + Potassium Chloride + Sodium Chloride) Multivitamins + Minerals - Tab (Biotin + Calcium D-Pantothenate + Calcium Phosphate (Dibasic) + Copper Sulfate + Dl-Alpha Tocopheryl Acetate + Ferrous Fumarate + Folic Acid + Magnesium Sulfate + Nicotinamide + Pyridoxine Hydrochloride + Thiamine Mononitrate + Vitamin a Palmitate + Vitamin B12 + Vitamin B2 + Vitamin C + Vitamin D3) Multivitamins and Minerals (Biotin + Calcium (Calcium Phosphate) + Copper (Copper Sulfate) + D-Pantothenic Acid (Calcium D-Pantothenate) + Folic Acid + Iron + Magnesium Sulfate + Nicotinamide + Phosphorus (Calcium Phosphate) + Vitamin a (Vitamin a Palmitate) + Vitamin B1 (Thiamine Mononitrate) + Vitamin B12 + Vitamin B2 + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C + Vitamin D + Vitamin E (D-Alpha Tocopheryl Acetate)) Nutravit Pst (Calcium D-Pantothenate + Folic Acid + Iodine (Potassium Iodide) + Iron (Iron Peptonized) + Magnesium Sulfate + Manganese (Manganese Sulfate) + Nicotinamide + Pyridoxine Hydrochloride + Thiamine Hydrochloride + Vitamin a + Vitamin B12 + Vitamin B2 + Vitamin D + Vitamin E) Poulti-Paste (Glycerine + Magnesium Sulfate + Methyl Salicylate) Poultice (Acetic Acid + Glycerine + Kaolin + Magnesium Sulfate + Menthol + Sodium Borate) Poultice - Pst (Acetic Acid + Kaolin + Magnesium Sulfate + Sodium Borate) Poultice Powder (Aluminum Potassium Sulfate + Bentonite + Magnesium Sulfate + Methyl Salicylate) Pro-Laxol Liq (Boldo + Cascara Sagrada + Magnesium Sulfate) Pro-Lyte (Calcium Chloride + Calcium D-Pantothenate + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Potassium Citrate + Potassium Phosphate Monobasic + Sodium Chloride + Sodium Phosphate Monobasic + Vitamin C) Ratanhia Comp. Drops (Calcium Fluoride + Esculin + Krameria (Triandra) + Magnesium Sulfate + Myrrh + Olea Europea Homeo Chemical + Silver Nitrate) Reducine Medicated Poultice Pst (Aluminum Ammonium Sulfate Dodecahydrate + Bentonite + Glycerine + Kaolin + Magnesium Sulfate + Methyl Salicylate + Peppermint Oil) Scarlet Pwr (Calcium Phosphate + Ethylenediamine Dihydroiodide + Fenugreek + Gentiana Lutea + Ginger + Iron Oxide + Linum Usitatissimum + Magnesium Carbonate + Magnesium Sulfate + Sodium Sulfate + Sodium Thiosulfate) Solution Carda (Magnesium Sulfate + Potassium Bicarbonate + Sodium Bicarbonate) Stress (Calcium Phosphate + Cobalt Sulfate + Copper Sulfate + Ferrous Gluconate + Magnesium Sulfate + Manganese Sulfate + Potassium Iodide + Sodium Phosphate Monobasic + Vitamin a + Vitamin D3 + Zinc Sulfate) Stv Amino Acid Sol Inj (Arginine Hcl + Calcium Chloride + Dexpanthenol + Dextrose + Dl-Methionine + Glutamic Acid + Histidine Hcl + Isoleucine + L-Cysteine Hydrochloride + L-Lysine Hydrochloride + Leucine + Magnesium Sulfate + Nicotinamide + Phenylalanine + Potassium Chloride + Pyridoxine Hydrochloride + Sodium Acetate + Threonine + Tryptophan + Valine + Vitamin B1 (Thiamine) + Vitamin B12 + Vitamin B2 (Riboflavin)) Super Multiple Vitamins and Min Tab (Biotin + Calcium (Calcium Phosphate) + Calcium D-Pantothenate + Copper (Copper Sulfate) + D-Alpha Tocopheryl Acetate + Folic Acid + Iron + Magnesium Sulfate + Nicotinamide + Phosphorus (Calcium Phosphate) + Vitamin a (Vitamin a Palmitate) + Vitamin B1 (Thiamine Mononitrate) + Vitamin B12 + Vitamin B2 + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C + Vitamin D) Tetra Fungistop (Magnesium Sulfate + Silver + Sodium Chloride)
Dantrium Intravenous
Formula chimica
C14H10N4O5
Dantrium Intravenous
RX link
http://www.rxlist.com/cgi/generic3/dantrolene.htm
Dantrium Intravenous
FDA foglio
Dantrium Intravenous
DMS (foglio di materiale di sicurezza)
Dantrium Intravenous
Sintesi di riferimento
Nessuna informazione disponibile
Dantrium Intravenous
Peso molecolare
314.253 g/mol
Dantrium Intravenous
Temperatura di fusione
279-280 oC
Dantrium Intravenous
H2O Solubilita
Bassa (146 mg / L)
Dantrium Intravenous
Stato
Solid
Dantrium Intravenous
LogP
1.506
Dantrium Intravenous
Forme di dosaggio
Capsula, polvere per soluzione
Dantrium Intravenous
Indicazione
Per l'uso, insieme con appropriate misure di sostegno, per la gestione del ipermetabolismo fulminante del muscolo scheletrico caratteristico delle crisi di ipertermia maligna in pazienti di ogni età. Anche utilizzata prima dell'intervento, e, a volte dopo l'intervento, per prevenire o attenuare la comparsa dei segni clinici e di laboratorio di ipertermia maligna in soggetti ritenuti ipertermia maligna sensibili.
Dantrium Intravenous
Farmacologia
Il dantrolene è classificato come un diretto effetto rilassante muscolare scheletrico. E 'attualmente l'unico trattamento specifico ed efficace per ipertermia maligna. In isolati preparato neuro-muscolare, Dantrium ha dimostrato di produrre rilassamento influenzando la risposta contrattile del muscolo in un luogo al di là della giunzione neuromuscolari. Nel muscolo scheletrico, Dantrium dissocia eccitazione-contrazione, probabilmente interferendo con il rilascio di Ca2 + dal reticolo sarcoplasmatico. In anestesia indotta sindrome ipertermia maligna, i punti di prova ad una intrinseca anormalità del muscolo scheletrico tessuti. Negli esseri umani selezionati, è stato ipotizzato che "gli elementi scatenanti" (ad esempio, anestetici generali e miorilassanti depolarizzanti) produrre un cambiamento all'interno della cellula che risulta in un calcio elevato mioplasmico. Questo calcio elevato mioplasmico attiva acuta processi cellulari catabolici che a cascata della crisi ipertermia maligna. Si ipotizza che oltre di Dantrium alla cella "innescato" maligno muscolare ipertermica ristabilisce un normale livello di calcio ionizzato nel mioplasma.
Dantrium Intravenous
Assorbimento
La biodisponibilità è del 70%.
Dantrium Intravenous
Tossicita
DL50 orale nei ratti è 7400 mg / kg. I sintomi che possono verificarsi in caso di sovradosaggio includono, ma non sono limitati a, debolezza muscolare e alterazioni dello stato di coscienza (per esempio, letargia, coma), vomito, diarrea e cristalluria.
Dantrium Intravenous
Informazioni paziente
Dantrium Intravenous
Atto interessato organismi
Gli esseri umani e altri mammiferi
