Dantrolene Sodium
Dantrolene Sodium Brand names, Dantrolene Sodium Analogs
Dantrolene Sodium Brand Names Mixture
- Acti Poultice (Eucalyptus Oil + Magnesium Sulfate + Menthol + Methyl Salicylate + Thymol)
- Agobyl Granule (Magnesium Sulfate + Peptone)
- Agobyl Liquide (Magnesium Sulfate + Peptone)
- Alsilax (Boldo + Cascara Sagrada + Magnesium Sulfate + Pancreatin + Peptone)
- Amino Acid Concentrate Inj (Arginine Hcl + Calcium Chloride + Dexpanthenol + Dextrose + Dl-Methionine + Glutamic Acid + Histidine Hcl + Isoleucine + L-Cysteine Hydrochloride + L-Lysine Hydrochloride + Leucine + Magnesium Sulfate + Nicotinamide + Phenylalanine + Potassium Chloride + Sodium Acetate + Threonine + Tryptophan + Valine + Vitamin B1 (Thiamine) + Vitamin B12 + Vitamin B2 (Riboflavin) + Vitamin B6 (Pyridoxine))
- Amino Acid Formula Inj (Alanine + Arginine + Calcium Chloride + Calcium D-Pantothenate + Dextrose + Dl-Methionine + Glutamic Acid + Glycine + Histidine + Isoleucine + L-Aspartic Acid + Leucine + Lysine + Magnesium Sulfate + Nicotinamide + Phenylalanine + Potassium Chloride + Proline + Pyridoxine Hydrochloride + Riboflavin 5'-Phosphate Sodium + Serine + Sodium Acetate + Sodium Glutamate + Thiamine Hydrochloride + Threonine + Tryptophan + Tyrosine + Valine + Vitamin B12)
- Amino Acid Formula Inj (Alanine + Arginine + Calcium Chloride + Calcium D-Pantothenate + Dextrose + Glutamic Acid + Glycine + Histidine + Isoleucine + L-Aspartic Acid + Leucine + Lysine + Magnesium Sulfate + Methionine + Nicotinamide + Phenylalanine + Potassium Chloride + Proline + Pyridoxine Hydrochloride + Riboflavin-5-Phosphate + Serine + Sodium Acetate + Sodium Glutamate + Thiamine Hydrochloride + Threonine + Tryptophan + Tyrosine + Valine + Vitamin B12)
- Amino Acid Inj (Arginine + Calcium Chloride + D-Pantothenic Acid (Calcium D-Pantothenate) + Dextrose + Histidine + Isoleucine + L-Cysteine Hydrochloride + Leucine + Lysine + Magnesium Sulfate + Methionine + Nicotinamide + Phenylalanine + Potassium Chloride + Pyridoxine Hydrochloride + Sodium Acetate + Threonine + Tryptophan + Valine + Vitamin B1 + Vitamin B12 + Vitamin B2)
- Amino Lite (Arginine + Calcium Chloride + Dextrose + Isoleucine + L-Cysteine Hydrochloride + L-Histidine Hcl + L-Lysine Hydrochloride + Leucine + Magnesium Sulfate + Methionine + Nicotinic Acid + Phenylalanine + Potassium Chloride + Pyridoxine Hydrochloride + Sodium Glutamate + Thiamine Hydrochloride + Threonine + Tryptophan + Valine + Vitamin B12 + Vitamin B2 (Riboflavin 5'-Phosphate Sodium))
- Amino Solution - Liq (Calcium Chloride + Calcium D-Pantothenate + Casein Hydrolysate + Dextrose + Magnesium Sulfate + Nicotinamide + Pyridoxine Hydrochloride + Sodium Acetate + Vitamin B1 (Acetiamine) + Vitamin B12 + Vitamin B2)
- Amino Solution Inj (Arginine + Calcium Chloride + Calcium D-Pantothenate + Dextrose + Dl-Methionine + Histidine + Isoleucine + Leucine + Lysine + Magnesium Sulfate + Nicotinamide + Phenylalanine + Sodium Acetate + Threonine + Tryptophan + Valine + Vitamin B1 + Vitamin B12 + Vitamin B2 + Vitamin B6)
- Anticoryzax (Calcium Lactophosphate + Magnesium Sulfate + Ribonucleic Acid + Vitamin C)
- Bvs Amino Acid Solution Inj (Arginine Hcl + Calcium Chloride + Dexpanthenol + Dextrose + Dl-Isoleucine + L-Cysteine Hydrochloride + L-Histidine Hcl + L-Lysine Hydrochloride + Leucine + Magnesium Sulfate + Methionine + Nicotinamide + Phenylalanine + Potassium Chloride + Pyridoxine Hydrochloride + Sodium Acetate Hemodialysis + Sodium Glutamate + Threonine + Tryptophan + Valine + Vitamin B1 + Vitamin B12 + Vitamin B2)
- Bylium Liq (Boldo + Cascara Sagrada + Magnesium Sulfate + Pancreatin + Peptone)
- Calcium Lactate Et Magnesium Sulfate (Calcium Lactate + Magnesium Sulfate)
- Calcium/Magnesium Drink (Calcium (Calcium Lactate, Calcium Carbonate, Calcium Glycerophosphate) + Magnesium (Magnesium Citrate, Magnesium Sulfate, Magnesium Oxide))
- Calf Electrolytes (Calcium Lactate + Ferrous Sulfate + Magnesium Sulfate + Potassium Chloride + Sodium Chloride + Vitamin a + Vitamin B12)
- Calf-Lyte (Calcium Chloride + Calcium D-Pantothenate + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Potassium Citrate + Potassium Phosphate Monobasic + Sodium Chloride + Sodium Phosphate Monobasic + Vitamin C)
- Disc-Discovery Tablets (Calcium (Calcium Phosphate (Dibasic), Calcium Ascorbate) + Magnesium (Magnesium Sulfate, Magnesium Oxide) + Manganese (Manganese Sulfate) + Potassium (Potassium Citrate) + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C (Ascorbic Acid, Calcium Ascorbate) + Vitamin D3 (Cholecalciferol) + Zinc Sulfate)
- Eau Purgative Riga (Magnesium Sulfate + Sodium Sulfate)
- Electrosul (Calcium Chloride + Calcium D-Pantothenate + Cobalt Sulfate + Copper Sulfate + Ferrous Sulfate + Magnesium Sulfate + Manganese Sulfate + Nicotinic Acid + Potassium Chloride + Sodium Chloride + Sulfamerazine Sodium + Sulfathiazole Sodium + Vitamin a + Vitamin B12 + Vitamin B2 + Vitamin D3 + Zinc Sulfate)
- Flex Capsules (Calcium (Calcium Ascorbate) + Magnesium Sulfate + Potassium (Potassium Sulfate))
- Formule 1705 - Liq (Magnesium Sulfate + Ox Bile Extract)
- Ion Aid (Calcium Gluconate + Dextrose + Glycine + Magnesium Sulfate + Potassium Phosphate Monobasic + Sodium Chloride)
- Laxabyl No109 (Barberry Root + Boldo + Cascara Sagrada + Magnesium Sulfate + Pancreatin + Peptone + Taraxacum Officinale Weber)
- Life Guard H E Pws (Calcium Phosphate (Dibasic) + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Sodium Bicarbonate + Sodium Chloride)
- Life Guard Oral (Calcium Phosphate (Dibasic) + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Protein + Sodium Bicarbonate + Sodium Chloride)
- Life Guard Pws Twin-Pak (Calcium Phosphate + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Protein + Sodium Bicarbonate + Sodium Chloride)
- Life-Guard H.E. Pwr (Calcium Phosphate + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Sodium Bicarbonate + Sodium Chloride)
- Magnesium Cap (Magnesium Oxide + Magnesium Sulfate)
- Magnesium Sulfate in 5%Dextrose Inj(20mg/Ml) (Dextrose + Magnesium Sulfate)
- Medi-3-Sulvita (Calcium Chloride + D-Pantothenic Acid + Magnesium Sulfate + Nicotinamide + Potassium Chloride + Sodium Acetate + Sodium Chloride + Sulfamerazine Sodium + Sulfamethazine Sodium + Sulfathiazole Sodium + Vitamin a + Vitamin B12 + Vitamin B2 + Vitamin D3)
- Multi-Vi-Min Capsules (Biotin + Chromium (Chromium Hvp Chelate) + D-Pantothenic Acid (Calcium D-Pantothenate) + Folic Acid + Iron (Ferric Ammonium Citrate) + Magnesium Sulfate + Manganese (Manganese Oxide) + Molybdenum (Sodium Molybdate) + Nicotinamide + Potassium (Potassium Chloride) + Selenium (Sodium Selenite) + Vitamin a (Vitamin a Palmitate) + Vitamin B1 (Thiamine Hydrochloride) + Vitamin B12 + Vitamin B2 (Riboflavin-5-Phosphate) + Vitamin B6 (Pyridoxal-5-Phosphate) + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C + Vitamin E (Dl-Alpha Tocopheryl Acetate) + Zinc Sulfate)
- Multiple Electrolyte Additive Inj (Calcium Gluconate + Magnesium Sulfate + Potassium Chloride + Sodium Chloride)
- Multivitamins + Minerals - Tab (Biotin + Calcium D-Pantothenate + Calcium Phosphate (Dibasic) + Copper Sulfate + Dl-Alpha Tocopheryl Acetate + Ferrous Fumarate + Folic Acid + Magnesium Sulfate + Nicotinamide + Pyridoxine Hydrochloride + Thiamine Mononitrate + Vitamin a Palmitate + Vitamin B12 + Vitamin B2 + Vitamin C + Vitamin D3)
- Multivitamins and Minerals (Biotin + Calcium (Calcium Phosphate) + Copper (Copper Sulfate) + D-Pantothenic Acid (Calcium D-Pantothenate) + Folic Acid + Iron + Magnesium Sulfate + Nicotinamide + Phosphorus (Calcium Phosphate) + Vitamin a (Vitamin a Palmitate) + Vitamin B1 (Thiamine Mononitrate) + Vitamin B12 + Vitamin B2 + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C + Vitamin D + Vitamin E (D-Alpha Tocopheryl Acetate))
- Nutravit Pst (Calcium D-Pantothenate + Folic Acid + Iodine (Potassium Iodide) + Iron (Iron Peptonized) + Magnesium Sulfate + Manganese (Manganese Sulfate) + Nicotinamide + Pyridoxine Hydrochloride + Thiamine Hydrochloride + Vitamin a + Vitamin B12 + Vitamin B2 + Vitamin D + Vitamin E)
- Poulti-Paste (Glycerine + Magnesium Sulfate + Methyl Salicylate)
- Poultice (Acetic Acid + Glycerine + Kaolin + Magnesium Sulfate + Menthol + Sodium Borate)
- Poultice - Pst (Acetic Acid + Kaolin + Magnesium Sulfate + Sodium Borate)
- Poultice Powder (Aluminum Potassium Sulfate + Bentonite + Magnesium Sulfate + Methyl Salicylate)
- Pro-Laxol Liq (Boldo + Cascara Sagrada + Magnesium Sulfate)
- Pro-Lyte (Calcium Chloride + Calcium D-Pantothenate + Dextrose + Glycine + Magnesium Sulfate + Potassium Chloride + Potassium Citrate + Potassium Phosphate Monobasic + Sodium Chloride + Sodium Phosphate Monobasic + Vitamin C)
- Ratanhia Comp. Drops (Calcium Fluoride + Esculin + Krameria (Triandra) + Magnesium Sulfate + Myrrh + Olea Europea Homeo Chemical + Silver Nitrate)
- Reducine Medicated Poultice Pst (Aluminum Ammonium Sulfate Dodecahydrate + Bentonite + Glycerine + Kaolin + Magnesium Sulfate + Methyl Salicylate + Peppermint Oil)
- Scarlet Pwr (Calcium Phosphate + Ethylenediamine Dihydroiodide + Fenugreek + Gentiana Lutea + Ginger + Iron Oxide + Linum Usitatissimum + Magnesium Carbonate + Magnesium Sulfate + Sodium Sulfate + Sodium Thiosulfate)
- Solution Carda (Magnesium Sulfate + Potassium Bicarbonate + Sodium Bicarbonate)
- Stress (Calcium Phosphate + Cobalt Sulfate + Copper Sulfate + Ferrous Gluconate + Magnesium Sulfate + Manganese Sulfate + Potassium Iodide + Sodium Phosphate Monobasic + Vitamin a + Vitamin D3 + Zinc Sulfate)
- Stv Amino Acid Sol Inj (Arginine Hcl + Calcium Chloride + Dexpanthenol + Dextrose + Dl-Methionine + Glutamic Acid + Histidine Hcl + Isoleucine + L-Cysteine Hydrochloride + L-Lysine Hydrochloride + Leucine + Magnesium Sulfate + Nicotinamide + Phenylalanine + Potassium Chloride + Pyridoxine Hydrochloride + Sodium Acetate + Threonine + Tryptophan + Valine + Vitamin B1 (Thiamine) + Vitamin B12 + Vitamin B2 (Riboflavin))
- Super Multiple Vitamins and Min Tab (Biotin + Calcium (Calcium Phosphate) + Calcium D-Pantothenate + Copper (Copper Sulfate) + D-Alpha Tocopheryl Acetate + Folic Acid + Iron + Magnesium Sulfate + Nicotinamide + Phosphorus (Calcium Phosphate) + Vitamin a (Vitamin a Palmitate) + Vitamin B1 (Thiamine Mononitrate) + Vitamin B12 + Vitamin B2 + Vitamin B6 (Pyridoxine Hydrochloride) + Vitamin C + Vitamin D)
- Tetra Fungistop (Magnesium Sulfate + Silver + Sodium Chloride)
Dantrolene Sodium Chemical_Formula
C14H10N4O5
Dantrolene Sodium RX_link
http://www.rxlist.com/cgi/generic3/dantrolene.htm
Dantrolene Sodium fda sheet
Dantrolene Sodium msds (material safety sheet)
Dantrolene Sodium Synthesis Reference
No information avaliable
Dantrolene Sodium Molecular Weight
314.253 g/mol
Dantrolene Sodium Melting Point
279-280 oC
Dantrolene Sodium H2O Solubility
Low (146 mg/L)
Dantrolene Sodium State
Solid
Dantrolene Sodium LogP
1.506
Dantrolene Sodium Dosage Forms
Capsule; Powder for solution
Dantrolene Sodium Indication
For use, along with appropriate supportive measures, for the management of the fulminant hypermetabolism of skeletal muscle characteristic of malignant hyperthermia crises in patients of all ages. Also used preoperatively, and sometimes postoperatively, to prevent or attenuate the development of clinical and laboratory signs of malignant hyperthermia in individuals judged to be malignant hyperthermia susceptible.
Dantrolene Sodium Pharmacology
Dantrolene is classified as a direct-acting skeletal muscle relaxant. It is currently the only specific and effective treatment for malignant hyperthermia. In isolated nerve-muscle preparation, Dantrium has been shown to produce relaxation by affecting the contractile response of the muscle at a site beyond the myoneural junction. In skeletal muscle, Dantrium dissociates excitation-contraction coupling, probably by interfering with the release of Ca2+ from the sarcoplasmic reticulum. In the anesthetic-induced malignant hyperthermia syndrome, evidence points to an intrinsic abnormality of skeletal muscle tissue. In selected humans, it has been postulated that “triggering agents” (e.g.,general anesthetics and depolarizing neuromuscular blocking agents) produce a change within the cell which results in an elevated myoplasmic calcium. This elevated myoplasmic calcium activates acute cellular catabolic processes that cascade to the malignant hyperthermia crisis. It is hypothesized that addition of Dantrium to the “triggered” malignant hyperthermic muscle cell reestablishes a normal level of ionized calcium in the myoplasm.
Dantrolene Sodium Absorption
Bioavailability is 70%.
Dantrolene Sodium side effects and Toxicity
Oral LD50 in rats is 7400 mg/kg. Symptoms which may occur in case of overdose include, but are not limited to, muscular weakness and alterations in the state of consciousness (e.g., lethargy, coma), vomiting, diarrhea, and crystalluria.
Dantrolene Sodium Patient Information
Dantrolene Sodium Organisms Affected
Humans and other mammals
