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• Anti-inflammatory Agents
• Nonsteroidal Antiinflammatory Agents (NSAIDs)
• ATC:M01AE12

• Alvo
• Daypro
• Daypro Alta
• Deflam
• Oxaprozin [Usan:Ban:Inn:Jan]
• Oxaprozina [Inn-Spanish]
• Oxaprozine
• Oxaprozine [Inn-French]
• Oxaprozinum [Inn-Latin]
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No information avaliable

C₁₈H₁₅NO₃

http://www.rxlist.com/cgi/generic/oxaproz.htm

Voir FDA

Voir MSDS

Aucune information disponible

293.317 g/mol

158 - 159 ^oC

Insolubles

Solid

4.8

Tablet

Utilisé pour soulager l'inflammation, l'enflure, la raideur et des douleurs articulaires associées à l'arthrite rhumatoïde et l'arthrose.

Oxaprozine est un médicament anti-inflammatoires non stéroïdiens (AINS) avec des propriétés analgésiques et antipyrétiques. Oxaprozine est utilisé pour traiter l'arthrite rhumatoïde, l'arthrose, la dysménorrhée, et pour soulager la douleur modérée.

Oxaprozine est de 95% après administration orale. Les aliments peuvent réduire le taux d'absorption de l'oxaprozine, mais le degré d'absorption est inchangé. Les antiacides ne modifient pas sensiblement l'ampleur et la vitesse d'absorption de l'oxaprozine.

Oral, souris: DL50 = 1210 mg / kg; orale, lapin: DL50 = 172 mg / kg; voie orale, rat: DL50 = 4470 mg / kg

Daypro, like other drugs of its class, can cause discomfort and, rarely, more serious side effects, such as gastrointestinal bleeding, which may result in hospitalization and even fatal outcomes. Although serious gastrointestinal tract ulcerations and bleeding can occur without warning symptoms, patients should be alert for the signs and symptoms of ulcerations and bleeding, and should ask for medical advice when observing any indicative sign or symptoms. Patients should be apprised of the importance of this follow-up.

Patients should report to their physicians the signs or symptoms of gastrointestinal ulceration or bleeding, skin rash, weight gain, or edema.

Patients should be informed of the warning signs and symptoms of hepatotoxicity (e.g., nausea, fatigue, lethargy, pruritus, jaundice, right upper quadrant tenderness, and “flu-like” symptoms). If these occur, patients should be instructed to stop therapy and seek immediate medical therapy.

Patients should also be instructed to seek immediate emergency help in the case of an anaphylactoid reaction.

In late pregnancy, as with other NSAIDs, Daypro should be avoided because it will cause premature closure of the ductus arteriosus.

Les humains et autres mammifères