Categorie
Kemadrin
Les marques,
Kemadrin
Analogs
Kemadrin
Les marques melange
No information avaliable
Kemadrin
Formule chimique
C19H29NO
Kemadrin
RX lien
No information avaliable
Kemadrin
FDA fiche
Kemadrin
msds (fiche de securite des materiaux)
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Synthese de reference
Adamson, le brevet américain. 2.891.890 (1959 à Burroughs Wellcome)
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Poids moleculaire
287.44 g/mol
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Point de fusion
86 oC
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H2O Solubilite
Modérément soluble dans l'eau, ~ 30 mg / ml
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Etat
Solid
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LogP
4.37
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Formes pharmaceutiques
Tablet; Elixir
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Indication
Pour le traitement de la maladie de Parkinson (surtout d'origine médicamenteuse)
Kemadrin
Pharmacologie
Procyclidine a une action semblable à l'atropine. C'est effets antispasmodiques sont pensés pour être lié à l'obstruction des récepteurs cholinergiques centraux M1, M2 et M4. Il est utilisé pour traiter la dysfonction parkinsonisme symptomatique et extrapyramidaux causés par les antipsychotiques.
Kemadrin
Absorption
Aucune information disponible
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Toxicite
DL50 = 60 mg / kg (IV chez la souris)
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Information pour les patients
Patient Information:
Follow your doctors instructions for taking this medicine. This medicine can be taken with food or a snack,
to minimize stomach upset. As your body becomes used to the medicine, it should be taken on an empty
stomach. Talk to your doctor about the best time of day to take the medicine. For patients taking the
extended-release forms, swallow the tablet whole, do NOT CRUSH or CHEW. You may break the tablet in half
if the whole pill is too large for you to take.
This medicine can cause dizziness or drowsiness. Be cautious when driving or performing other hazardous
activities. This medicine can impair judgment. Do NOT increase your dose of this medicine without first
talking to your doctor, even if you feel that the medicine is not working.
Discuss the risks and benefits of using this medicine during pregnancy. It is unknown whether this medicine
is excreted in breast milk. DO NOT breastfeed while taking this medicine until you have talked to your
doctor or pediatrician.
Kemadrin
Organismes affectes
Les humains et autres mammifères