ULR
Categoria
ULR Nombres de marca, ULR Analogos
ULR Marca los nombres de mezcla
ULR Formula quimica
C9H13NO
ULR RX enlace
No information avaliable
ULR FDA hoja
ULR MSDS (hoja de seguridad de materiales)
ULR Sintesis de referencia
Vanderbitle, Hass, Ind. Eng.. Chem. 32, 34 (1940)
ULR Peso molecular
151.206 g/mol
ULR Punto de fusion
190-194 oC
ULR H2O Solubilidad
Muy soluble
ULR Estado
Solid
ULR LogP
0.974
ULR Formas de dosificacion
Tableta, inyección, jarabe
ULR Indicacion
Para el tratamiento de la congestión nasal, el control de la incontinencia urinaria, priapismo y la obesidad.
ULR Farmacologia
La fenilpropanolamina (PPA), un agente simpaticomimético de estructura similar a la pseudoefedrina, se utiliza para tratar la congestión nasal. La fenilpropanolamina se encuentra en las formulaciones de supresor del apetito y con guaifenesinin en las formulaciones de frío para la tos. En 2000, la FDA solicitó que todas las compañías farmacéuticas suspender la comercialización de productos que contienen fenilpropanolamina, debido a un mayor riesgo de ictus hemorrágico en las mujeres que utilizan la fenilpropanolamina.
ULR Absorcion
Reducción de la biodisponibilidad (38%) del tracto gastrointestinal debido al metabolismo de primer paso por la monoaminooxidasa en el estómago y el hígado.
ULR Toxicidad
Puede provocar extrasístoles ventriculares y paroxismos cortos de taquicardia ventricular, una sensación de plenitud en la cabeza y hormigueo en las extremidades; LD50 = 1490mg/kg (por vía oral en ratas)
ULR Informacion de Pacientes
PATIENT INFORMATION
Description
--------------------------------------------------------------------------------
This medicine is used to treat nasal congestion caused by colds or hay fever. Your doctor may prescribe this medicine for
other conditions as well.
General Information
--------------------------------------------------------------------------------
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in
this database. If you have questions about your medicines, talk to your healthcare provider.
Proper use of this medicine
--------------------------------------------------------------------------------
For proper use of this medicine, follow the directions on the package, unless otherwise instructed by your doctor. To use
a nose spray: gently blow your nose. Then sit back and tilt your head back slightly. Place the tip of the spray container
into the nose. Close off the other nostril with your other hand. Spray into the nose. Wait at least one minute in between
sprays. After using, rinse the tip of the sprayer in hot water and dry. This prevents contamination.
Missed Dose
--------------------------------------------------------------------------------
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your
regular schedule. Do not double doses.
Storage
--------------------------------------------------------------------------------
Follow package directions for proper storage. Keep away from heat, moisture or light.
Possible Side Effects
--------------------------------------------------------------------------------
Some common side effects reported with this medicine include:
stinging
burning
sneezing
increase in nasal discharge
If you experience other bothersome side effects, talk to your health care provider.
Some common side effects with this medicine include:
burning or stinging inside your nose
confusion
nervousness
headache
nausea
vomiting
Report any of the following to your doctor:
dizziness
or fainting spells
difficulty breathing
chest pain
rapid heart beat
increased sweating
tingling or numbness in the hands or feet
Warnings/Precautions
--------------------------------------------------------------------------------
Do NOT use more that the recommended dose of this medicine.
Do NOT use more of this medicine or longer than prescribed.
Using this medicine longer that 3-5 days can cause a condition known as "rebound congestion".
Overdose
--------------------------------------------------------------------------------
Seek medical attention immediately. For non emergencies, contact your local or regional poison control center
Drug Interactions
--------------------------------------------------------------------------------
This medicine can cause in increase in toxic effects to the heart when taken with other stimulants. Avoid taking with:
theophylline
digoxin
general anesthetics
atropine
MAO inhibitors.
Taking this medicine with the following herbs can cause increased side effects including high blood pressure and should be
avoided:
ephedra
yohimbe
This medicine can interact with the following drugs:
atropine
bromocriptine
diuretics (water pills)
linezolid
maprotiline
drugs used for depression
high blood pressure medications
drugs used for migraine headaches
oxytocin
vasopressin
For more information on specific drug interactions, talk to your doctor or pharmacist.
Pregnancy/Nursing
--------------------------------------------------------------------------------
Talk to your doctor about using this medicine during pregnancy or nursing to discuss any possible risks to you or your baby.
More Information
--------------------------------------------------------------------------------
For more information about this medicine, talk to your healthcare provider.
Description
--------------------------------------------------------------------------------
This medicine is used to treat nasal congestion caused by colds or hay fever. Your doctor may prescribe this medicine for
other conditions as well.
General Information
--------------------------------------------------------------------------------
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in
this database. If you have questions about your medicines, talk to your healthcare provider.
Proper use of this medicine
--------------------------------------------------------------------------------
For proper use of this medicine, follow the directions on the package, unless otherwise instructed by your doctor. To use
a nose spray: gently blow your nose. Then sit back and tilt your head back slightly. Place the tip of the spray container
into the nose. Close off the other nostril with your other hand. Spray into the nose. Wait at least one minute in between
sprays. After using, rinse the tip of the sprayer in hot water and dry. This prevents contamination.
Missed Dose
--------------------------------------------------------------------------------
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your
regular schedule. Do not double doses.
Storage
--------------------------------------------------------------------------------
Follow package directions for proper storage. Keep away from heat, moisture or light.
Possible Side Effects
--------------------------------------------------------------------------------
Some common side effects reported with this medicine include:
stinging
burning
sneezing
increase in nasal discharge
If you experience other bothersome side effects, talk to your health care provider.
Some common side effects with this medicine include:
burning or stinging inside your nose
confusion
nervousness
headache
nausea
vomiting
Report any of the following to your doctor:
dizziness
or fainting spells
difficulty breathing
chest pain
rapid heart beat
increased sweating
tingling or numbness in the hands or feet
Warnings/Precautions
--------------------------------------------------------------------------------
Do NOT use more that the recommended dose of this medicine.
Do NOT use more of this medicine or longer than prescribed.
Using this medicine longer that 3-5 days can cause a condition known as "rebound congestion".
Overdose
--------------------------------------------------------------------------------
Seek medical attention immediately. For non emergencies, contact your local or regional poison control center
Drug Interactions
--------------------------------------------------------------------------------
This medicine can cause in increase in toxic effects to the heart when taken with other stimulants. Avoid taking with:
theophylline
digoxin
general anesthetics
atropine
MAO inhibitors.
Taking this medicine with the following herbs can cause increased side effects including high blood pressure and should be
avoided:
ephedra
yohimbe
This medicine can interact with the following drugs:
atropine
bromocriptine
diuretics (water pills)
linezolid
maprotiline
drugs used for depression
high blood pressure medications
drugs used for migraine headaches
oxytocin
vasopressin
For more information on specific drug interactions, talk to your doctor or pharmacist.
Pregnancy/Nursing
--------------------------------------------------------------------------------
Talk to your doctor about using this medicine during pregnancy or nursing to discuss any possible risks to you or your baby.
More Information
--------------------------------------------------------------------------------
For more information about this medicine, talk to your healthcare provider.
ULR Organismos afectados
Humanos y otros mamíferos
