Risperdal
Categoria
Risperdal Nombres de marca, Risperdal Analogos
Risperdal Marca los nombres de mezcla
Risperdal Formula quimica
C23H27FN4O2
Risperdal RX enlace
http://www.rxlist.com/cgi/generic/risperid.htm
Risperdal FDA hoja
Risperdal MSDS (hoja de seguridad de materiales)
Risperdal Sintesis de referencia
LEJ Kennis, J. Vandenberk, EE.UU. Pat. 4,804,663 (1989)
Risperdal Peso molecular
410.485 g/mol
Risperdal Punto de fusion
170oC
Risperdal H2O Solubilidad
2.8mg / L
Risperdal Estado
Solid
Risperdal LogP
2.718
Risperdal Formas de dosificacion
Tableta, solución (oral)
Risperdal Indicacion
Para el tratamiento de la esquizofrenia.
Risperdal Farmacologia
La risperidona es un medicamento antipsicótico atípico. Con mayor frecuencia se utiliza para tratar la psicosis delirante (como la esquizofrenia), pero risperidona también se utiliza para tratar algunas formas de trastorno bipolar y depresión psicótica. También se ha demostrado cierto éxito en el tratamiento de los síntomas del síndrome de Asperger y el autismo. La risperidona es ahora el medicamento antipsicótico más comúnmente recetados en los Estados Unidos. .
Risperdal Absorcion
Se absorbe bien. La biodisponibilidad oral absoluta de risperidona es del 70% (CV = 25%). La biodisponibilidad relativa de la risperidona oral de un comprimido es del 94% (CV = 10%) en comparación con una solución.
Risperdal Toxicidad
Los síntomas de sobredosis incluyen somnolencia, sedación, taquicardia, hipotensión y síntomas extrapiramidales. LD50 = 82.1mg/kg (por vía oral en ratones).
Risperdal Informacion de Pacientes
PATIENT INFORMATION
Physicians are advised to discuss the following issues with patients for whom they prescribe RISPERDAL�:
Orthostatic Hypotension
Patients should be advised of the risk of orthostatic hypotension, especially during the period of initial
dose titration.
Interference With Cognitive and Motor Performance
Since RISPERDAL� has the potential toimpair judgment, thinking, or motor skills, patients should be cautioned
about operating hazardous machinery, including automobiles, until they are reasonably certain that RISPERDAL�
therapy does not affect them adversely.
Pregnancy
Patients should be advised to notify their physician if they become pregnant or intend to become pregnant during
therapy.
Nursing
Patients should be advised not to breast-feed an infant if they are taking RISPERDAL.
Physicians are advised to discuss the following issues with patients for whom they prescribe RISPERDAL�:
Orthostatic Hypotension
Patients should be advised of the risk of orthostatic hypotension, especially during the period of initial
dose titration.
Interference With Cognitive and Motor Performance
Since RISPERDAL� has the potential toimpair judgment, thinking, or motor skills, patients should be cautioned
about operating hazardous machinery, including automobiles, until they are reasonably certain that RISPERDAL�
therapy does not affect them adversely.
Pregnancy
Patients should be advised to notify their physician if they become pregnant or intend to become pregnant during
therapy.
Nursing
Patients should be advised not to breast-feed an infant if they are taking RISPERDAL.
Risperdal Organismos afectados
Humanos y otros mamíferos
