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  • Cardyl Formula quimica

    C33H35FN2O5

    Cardyl RX enlace

    http://www.rxlist.com/cgi/generic/atorvastatin.htm

    Cardyl FDA hoja

    Cardyl FDA

    Cardyl MSDS (hoja de seguridad de materiales)

    Cardyl MSDS

    Cardyl Sintesis de referencia

    BD Roth, EE.UU. Pat. 5273, 995 (1991, 1993)

    Cardyl Peso molecular

    558.64 g/mol

    Cardyl Punto de fusion

    159.2-160.7oC

    Cardyl H2O Solubilidad

    Sodio soluble en agua salada, el 20,4 ug / ml (pH 2,1), 1,23 mg / ml (pH 6,0)

    Cardyl Estado

    Solid

    Cardyl LogP

    6.259

    Cardyl Formas de dosificacion

    Comprimido (10 mg, 20 mg o 40 mg)

    Cardyl Indicacion

    Para la gestión como un complemento a la dieta para reducir los niveles de C-total, LDL-C, apo B, y los niveles de TG en pacientes con hipercolesterolemia primaria y dislipidemia mixta.

    Cardyl Farmacologia

    Atorvastatina, un selectivo y competitivo de la HMG-CoA reductasa, se utiliza para reducir el colesterol y los triglicéridos en pacientes con hipercolesterolemia y dislipidemia mixta y en el tratamiento de homocigotos hipercolesterolemia familiar. Atorvastatina tiene una estructura única, larga vida media, y la selectividad hepática, que explica su mayor potencia de disminución de LDL en comparación con otros inhibidores de la HMG-CoA reductasa.

    Cardyl Absorcion

    La atorvastatina se absorbe rápidamente tras la administración oral. La biodisponibilidad absoluta de atorvastatina (droga madre) es de aproximadamente 14% y la disponibilidad sistémica de inhibidores de la HMG-CoA reductasa actividad inhibitoria es de aproximadamente 30%.

    Cardyl Toxicidad

    Rabdomiolisis, hemorragias oculares, y problemas hepáticos.

    Cardyl Informacion de Pacientes

    Lipitor is a HMG-CoA Reductase Inhibitor, also known as a statin. This class
    of treatments for high cholesterol is fairly new, and appears to work by
    blocking a liver enzyme which generates cholesterol. This medication appears
    to be the most effective in this class of drugs at lowering unhealthy LDL
    (low-density lipoprotein) cholesterol levels, in some cases up to 51%. It
    can be virtually as effective as an angioplasty in treating stable coronary
    artery disease. Currently, this drug is approved for use in patients with
    high cholesterol (hypercholesterolemia) due to high LDL levels, hereditary
    elevated fat levels (dysbetalipoproteinemia), familial high cholesterol,
    and to increase HDL (high-density lipoprotein) levels in patients with high
    cholesterol and those with both high cholesterol and high triglycerides (mixed
    dyslipidemia). Other accepted uses include the treatment of stable coronary
    artery diseas, preventing coronary heart disease, preventing clogged stents
    (tubes) placed in coronary arteries after surgery, preventing bone loss in
    type two diabetics, stabilizing lipid levels that have been altered by treatment
    with protease inhibitors. This treatment should be considered a last resort.
    The best way to lower cholesterol is through a program of healthy diet and
    exercise, and these should be maintained during treatment with Lipitor.

    Cardyl Organismos afectados

    Humanos y otros mamíferos