antiCD11 alpha
antiCD11 alpha Brand names, antiCD11 alpha Analogs
antiCD11 alpha Brand Names Mixture
- No information avaliable
antiCD11 alpha Chemical_Formula
No information avaliable
antiCD11 alpha RX_link
http://www.rxlist.com/cgi/generic3/raptiva.htm
antiCD11 alpha fda sheet
antiCD11 alpha msds (material safety sheet)
antiCD11 alpha Synthesis Reference
sequence listed in Werther WA, Gonzalez TN, O'Connor SJ, McCabe S, Chan B, Hotaling T, Champe M, Fox JA, Jardieu PM, Berman PW, Presta LG. Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1. J Immunol. 1996 Dec 1;157(11):4986-95
antiCD11 alpha Molecular Weight
No information avaliable
antiCD11 alpha Melting Point
61 oC (FAB fragment), 71 oC (whole mAb)-Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
antiCD11 alpha H2O Solubility
No information avaliable
antiCD11 alpha State
Liquid
antiCD11 alpha LogP
No information avaliable
antiCD11 alpha Dosage Forms
Solution (Subcutaneous Injection)
antiCD11 alpha Indication
For treatment of psoriasis
antiCD11 alpha Pharmacology
Lymphocyte activation and trafficking to skin play a role in the pathophysiology of chronic plaque psoriasis. In psoriatic skin, ICAM-1 cell surface expression is upregulated on endothelium and keratinocytes. Raptiva inhibits the binding of LFA-1 to the intercellular adhesion molecule-1 (ICAM-1), thereby inhibiting the adhesion of leukocytes to other cell types.
antiCD11 alpha Absorption
No information avaliable
antiCD11 alpha side effects and Toxicity
No information avaliable
antiCD11 alpha Patient Information
BIOD00074.html
antiCD11 alpha Organisms Affected
Humans and other mammals
