Zometa
Zometa Brand names, Zometa Analogs
Zometa Brand Names Mixture
- No information avaliable
Zometa Chemical_Formula
C16H13N3O3
Zometa RX_link
http://www.rxlist.com/cgi/generic3/mebend.htm
Zometa fda sheet
Zometa msds (material safety sheet)
Zometa Synthesis Reference
No information avaliable
Zometa Molecular Weight
295.293 g/mol
Zometa Melting Point
288.5 oC
Zometa H2O Solubility
71.3 mg/L
Zometa State
Solid
Zometa LogP
3.291
Zometa Dosage Forms
Paste; Powder; 100 mg chewable tablets
Zometa Indication
For the treatment of Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections.
Zometa Pharmacology
Mebendazole is a (synthetic) broad-spectrum anthelmintic. The principal mode of action for albendazole is by its inhibitory effect on tubulin polymerization which results in the loss of cytoplasmic microtubules.
Zometa Absorption
Poorly absorbed (approximately 5 to 10%) from gastrointestinal tract. Fatty food increases absorption.
Zometa side effects and Toxicity
Acute oral toxicity (LD50): 620 mg/kg [Mouse]. Symptoms of overdose include elevated liver enzymes, headaches, hair loss, low levels of white blood cells (neutropenia), fever, and itching.
Zometa Patient Information
Zometa Organisms Affected
Helminthic Microorganisms
