Zoledronic acid
Brand names,
Zoledronic acid
Analogs
Zoledronic acid
Brand Names Mixture
Zoledronic acid
Chemical_Formula
C16H13N3O3
Zoledronic acid
RX_link
http://www.rxlist.com/cgi/generic3/mebend.htm
Zoledronic acid
fda sheet
Zoledronic acid
msds (material safety sheet)
Zoledronic acid
Synthesis Reference
No information avaliable
Zoledronic acid
Molecular Weight
295.293 g/mol
Zoledronic acid
Melting Point
288.5 oC
Zoledronic acid
H2O Solubility
71.3 mg/L
Zoledronic acid
State
Solid
Zoledronic acid
LogP
3.291
Zoledronic acid
Dosage Forms
Paste; Powder; 100 mg chewable tablets
Zoledronic acid
Indication
For the treatment of Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections.
Zoledronic acid
Pharmacology
Mebendazole is a (synthetic) broad-spectrum anthelmintic. The principal mode of action for albendazole is by its inhibitory effect on tubulin polymerization which results in the loss of cytoplasmic microtubules.
Zoledronic acid
Absorption
Poorly absorbed (approximately 5 to 10%) from gastrointestinal tract. Fatty food increases absorption.
Zoledronic acid
side effects and Toxicity
Acute oral toxicity (LD50): 620 mg/kg [Mouse]. Symptoms of overdose include elevated liver enzymes, headaches, hair loss, low levels of white blood cells (neutropenia), fever, and itching.
Zoledronic acid
Patient Information
Zoledronic acid
Organisms Affected
Helminthic Microorganisms