Zevalin (IDEC Pharmaceuticals)
Brand names,
Zevalin (IDEC Pharmaceuticals)
Analogs
Zevalin (IDEC Pharmaceuticals)
Brand Names Mixture
Zevalin (IDEC Pharmaceuticals)
Chemical_Formula
C6382H9830N1672O1979S54
Zevalin (IDEC Pharmaceuticals)
RX_link
http://www.rxlist.com/cgi/generic3/zevalin.htm
Zevalin (IDEC Pharmaceuticals)
fda sheet
Zevalin (IDEC Pharmaceuticals)
msds (material safety sheet)
Zevalin (IDEC Pharmaceuticals)
Synthesis Reference
No information avaliable
Zevalin (IDEC Pharmaceuticals)
Molecular Weight
143375.5
Zevalin (IDEC Pharmaceuticals)
Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Zevalin (IDEC Pharmaceuticals)
H2O Solubility
No information avaliable
Zevalin (IDEC Pharmaceuticals)
State
Liquid
Zevalin (IDEC Pharmaceuticals)
LogP
-0.359
Zevalin (IDEC Pharmaceuticals)
Dosage Forms
Solution (IV Infusion)
Zevalin (IDEC Pharmaceuticals)
Indication
For treatment of non-Hodgkin's lymphoma
Zevalin (IDEC Pharmaceuticals)
Pharmacology
Zevalin binds to the CD20 antigen, which is predominantly expressed on mature B cells and on >90% of B-cell non-Hodgkin's lympohomas. The antibody leads to selective killing of B-cells.
Zevalin (IDEC Pharmaceuticals)
Absorption
No information avaliable
Zevalin (IDEC Pharmaceuticals)
side effects and Toxicity
No information avaliable
Zevalin (IDEC Pharmaceuticals)
Patient Information
No information avaliable
Zevalin (IDEC Pharmaceuticals)
Organisms Affected
Humans and other mammals