Ig gamma-2A chain C region, membrane-bound form
Brand names,
Ig gamma-2A chain C region, membrane-bound form
Analogs
Ig gamma-2A chain C region, membrane-bound form
Brand Names Mixture
Ig gamma-2A chain C region, membrane-bound form
Chemical_Formula
C6382H9830N1672O1979S54
Ig gamma-2A chain C region, membrane-bound form
RX_link
http://www.rxlist.com/cgi/generic3/zevalin.htm
Ig gamma-2A chain C region, membrane-bound form
fda sheet
Ig gamma-2A chain C region, membrane-bound form
msds (material safety sheet)
Ig gamma-2A chain C region, membrane-bound form
Synthesis Reference
No information avaliable
Ig gamma-2A chain C region, membrane-bound form
Molecular Weight
143375.5
Ig gamma-2A chain C region, membrane-bound form
Melting Point
61 oC (FAB fragment), 71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Ig gamma-2A chain C region, membrane-bound form
H2O Solubility
No information avaliable
Ig gamma-2A chain C region, membrane-bound form
State
Liquid
Ig gamma-2A chain C region, membrane-bound form
LogP
-0.359
Ig gamma-2A chain C region, membrane-bound form
Dosage Forms
Solution (IV Infusion)
Ig gamma-2A chain C region, membrane-bound form
Indication
For treatment of non-Hodgkin's lymphoma
Ig gamma-2A chain C region, membrane-bound form
Pharmacology
Zevalin binds to the CD20 antigen, which is predominantly expressed on mature B cells and on >90% of B-cell non-Hodgkin's lympohomas. The antibody leads to selective killing of B-cells.
Ig gamma-2A chain C region, membrane-bound form
Absorption
No information avaliable
Ig gamma-2A chain C region, membrane-bound form
side effects and Toxicity
No information avaliable
Ig gamma-2A chain C region, membrane-bound form
Patient Information
No information avaliable
Ig gamma-2A chain C region, membrane-bound form
Organisms Affected
Humans and other mammals