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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C15H13FO2
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RX_link
http://www.rxlist.com/cgi/generic2/flurbipro.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
244.261 g/mol
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Melting Point
110-111 oC
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H2O Solubility
8 mg/L
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State
Solid
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LogP
4.078
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Dosage Forms
Capsule (sustained-release); Liquid; Tablet
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Indication
Flurbiprofen tablets are indicated for the acute or long-term treatment of the signs and symptoms of rheumatoid arthritis and osteorarthritis.
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Pharmacology
Flurbiprofen, a nonsteroidal antiinflammatory drug (NSAID) of the propionic acid class, is used for the relief of pain and inflammation associated with rheumatoid arthritis and osteoarthritis and for the inhibition of intraoperative miosis. Flurbiprofen exhibits antiinflammatory, analgesic, and antipyretic activities.
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Absorption
The mean oral bioavailability of flurbiprofen from tablets is 96% relative to an oral solution.
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side effects and Toxicity
LD50=10 mg/kg (orally in dogs).
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Patient Information
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Organisms Affected
Humans and other mammals