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Xalatan Brand names, Xalatan Analogs

Xalatan Brand Names Mixture

  • No information avaliable

Xalatan Chemical_Formula

C7H15NO3

Xalatan RX_link

http://www.rxlist.com/cgi/generic3/carnitor.htm

Xalatan fda sheet

Xalatan FDA

Xalatan msds (material safety sheet)

Xalatan MSDS

Xalatan Synthesis Reference

No information avaliable

Xalatan Molecular Weight

161.199 g/mol

Xalatan Melting Point

196-197 oC

Xalatan H2O Solubility

2500 mg/mL

Xalatan State

Solid

Xalatan LogP

No information avaliable

Xalatan Dosage Forms

Liquid; Solution; Tablet

Xalatan Indication

For treatment of primary systemic carnitine deficiency, a genetic impairment of normal biosynthesis or utilization of levocarnitine from dietary sources, or for the treatment of secondary carnitine deficiency resulting from an inborn error of metabolism such as glutaric aciduria II, methyl malonic aciduria, propionic acidemia, and medium chain fatty acylCoA dehydrogenase deficiency. Used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias. Parenteral levocarnitine is indicated for the prevention and treatment of carnitine deficiency in patients with end-stage renal disease.

Xalatan Pharmacology

Levocarnitine is a carrier molecule in the transport of long chain fatty acids across the inner mitochondrial membrane. It also exports acyl groups from subcellular organelles and from cells to urine before they accumulate to toxic concentrations. Lack of carnitine can lead to liver, heart, and muscle problems. Carnitine deficiency is defined biochemically as abnormally low plasma concentrations of free carnitine, less than 20 µmol/L at one week post term and may be associated with low tissue and/or urine concentrations. Further, this condition may be associated with a plasma concentration ratio of acylcarnitine/levocarnitine greater than 0.4 or abnormally elevated concentrations of acylcarnitine in the urine. Only the L isomer of carnitine (sometimes called vitamin BT) affects lipid metabolism. The "vitamin BT" form actually contains D,L-carnitine, which competitively inhibits levocarnitine and can cause deficiency. Levocarnitine can be used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.

Xalatan Absorption

Absolute bioavailability is 15% (tablets or solution).

Xalatan side effects and Toxicity

LD50 > 8g/kg (mouse, oral). Adverse effects include hypertension, fever, tachycardia and seizures.

Xalatan Patient Information

Xalatan Organisms Affected

Humans and other mammals