Uricase
Brand names,
Uricase
Analogs
Uricase
Brand Names Mixture
Uricase
Chemical_Formula
C1521H2381N417O461S7
Uricase
RX_link
http://www.rxlist.com/cgi/generic3/elitek.htm
Uricase
fda sheet
Uricase
msds (material safety sheet)
Uricase
Synthesis Reference
No information avaliable
Uricase
Molecular Weight
34109.5
Uricase
Melting Point
No information avaliable
Uricase
H2O Solubility
No information avaliable
Uricase
State
Liquid
Uricase
LogP
-0.465
Uricase
Dosage Forms
Powder for solution
Uricase
Indication
For treatment of hyperuricemia, reduces elevated plasma uric acid levels (from chemotherapy)
Uricase
Pharmacology
Drugs used to treat lympohoid leukemia, non-Hodgkin's lymphoma and acute myelogenous leukemia often lead to the accumulation of toxic plasma levels of purine metabolites (i.e. uric acid). The injection of rasburicase reduces levels of uric acid and mitigates the toxic effects of chemotherapy induced tumor lysis.
Uricase
Absorption
No information avaliable
Uricase
side effects and Toxicity
No information avaliable
Uricase
Patient Information
No information avaliable
Uricase
Organisms Affected
Humans and other mammals