Urate oxidase
Brand names,
Urate oxidase
Analogs
Urate oxidase
Brand Names Mixture
Urate oxidase
Chemical_Formula
C1521H2381N417O461S7
Urate oxidase
RX_link
http://www.rxlist.com/cgi/generic3/elitek.htm
Urate oxidase
fda sheet
Urate oxidase
msds (material safety sheet)
Urate oxidase
Synthesis Reference
No information avaliable
Urate oxidase
Molecular Weight
34109.5
Urate oxidase
Melting Point
No information avaliable
Urate oxidase
H2O Solubility
No information avaliable
Urate oxidase
State
Liquid
Urate oxidase
LogP
-0.465
Urate oxidase
Dosage Forms
Powder for solution
Urate oxidase
Indication
For treatment of hyperuricemia, reduces elevated plasma uric acid levels (from chemotherapy)
Urate oxidase
Pharmacology
Drugs used to treat lympohoid leukemia, non-Hodgkin's lymphoma and acute myelogenous leukemia often lead to the accumulation of toxic plasma levels of purine metabolites (i.e. uric acid). The injection of rasburicase reduces levels of uric acid and mitigates the toxic effects of chemotherapy induced tumor lysis.
Urate oxidase
Absorption
No information avaliable
Urate oxidase
side effects and Toxicity
No information avaliable
Urate oxidase
Patient Information
No information avaliable
Urate oxidase
Organisms Affected
Humans and other mammals