Trilostane
Trilostane Brand names, Trilostane Analogs
Trilostane Brand Names Mixture
- No information avaliable
Trilostane Chemical_Formula
C20H27NO3
Trilostane RX_link
No information avaliable
Trilostane fda sheet
Trilostane msds (material safety sheet)
Trilostane Synthesis Reference
No information avaliable
Trilostane Molecular Weight
329.433 g/mol
Trilostane Melting Point
264 oC
Trilostane H2O Solubility
No information avaliable
Trilostane State
Solid
Trilostane LogP
2.635
Trilostane Dosage Forms
Capsules
Trilostane Indication
Used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
Trilostane Pharmacology
Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland. This product was withdrawn from the U.S. market in April 1994.
Trilostane Absorption
No information avaliable
Trilostane side effects and Toxicity
Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.
Trilostane Patient Information
No information avaliable
Trilostane Organisms Affected
Humans and other mammals
