Tarka
Brand names,
Tarka
Analogs
Tarka
Brand Names Mixture
Tarka
Chemical_Formula
C20H27NO3
Tarka
RX_link
No information avaliable
Tarka
fda sheet
Tarka
msds (material safety sheet)
Tarka
Synthesis Reference
No information avaliable
Tarka
Molecular Weight
329.433 g/mol
Tarka
Melting Point
264 oC
Tarka
H2O Solubility
No information avaliable
Tarka
State
Solid
Tarka
LogP
2.635
Tarka
Dosage Forms
Capsules
Tarka
Indication
Used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
Tarka
Pharmacology
Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland. This product was withdrawn from the U.S. market in April 1994.
Tarka
Absorption
No information avaliable
Tarka
side effects and Toxicity
Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.
Tarka
Patient Information
No information avaliable
Tarka
Organisms Affected
Humans and other mammals