Tositumomab
Tositumomab Brand names, Tositumomab Analogs
Tositumomab Brand Names Mixture
- No information avaliable
Tositumomab Chemical_Formula
C6416H9874N1688O1987S44
Tositumomab RX_link
http://www.rxlist.com/cgi/generic3/bexxar.htm
Tositumomab fda sheet
Tositumomab msds (material safety sheet)
Tositumomab Synthesis Reference
No information avaliable
Tositumomab Molecular Weight
143859.7
Tositumomab Melting Point
61 oC (FAB fragment), 71 oC (whole mAb)-Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Tositumomab H2O Solubility
No information avaliable
Tositumomab State
Liquid
Tositumomab LogP
-0.414
Tositumomab Dosage Forms
Solution (IV Infusion)
Tositumomab Indication
For treatment of non-Hodgkin's lymphoma (CD20 positive, follicular)
Tositumomab Pharmacology
Bexxar binds to the CD20 antigen, which is predominantly expressed on mature B cells and on >90% of B-cell non-Hodgkin??™s lympohomas. The antibody leads to selective killing of B-cells.
Tositumomab Absorption
No information avaliable
Tositumomab side effects and Toxicity
No information avaliable
Tositumomab Patient Information
No information avaliable
Tositumomab Organisms Affected
Humans and other mammals
