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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C26H35F3O6
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RX_link
http://www.rxlist.com/cgi/generic2/travoprost.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
500.548 g/mol
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Melting Point
No information avaliable
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H2O Solubility
>16 mg/ml at 25.0°C
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State
Liquid
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LogP
3.725
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Dosage Forms
Sterile ophthalmic solution (0.004%) with a pH of approximately 6.0 and an osmolality of approximately 290 mosmol/kg.
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Indication
Ophthalmic solution used for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication.
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Pharmacology
Travoprost, an isopropyl ester prodrug, is a synthetic prostaglandin F2α analogue. Travoprost reduces pressure in the eye by increasing the amount of fluid that drains from the eye.
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Absorption
Systemically absorbed when administered to the eye.
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side effects and Toxicity
Symptoms of overexposure include irritation to the skin, eyes, nose, throat, and respiratory tract.
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals