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Togamycin Brand names, Togamycin Analogs

Togamycin Brand Names Mixture

  • No information avaliable

Togamycin Chemical_Formula


Togamycin RX_link

Togamycin fda sheet

Togamycin FDA

Togamycin msds (material safety sheet)

Togamycin MSDS

Togamycin Synthesis Reference

No information avaliable

Togamycin Molecular Weight

351.463 g/mol

Togamycin Melting Point

No information avaliable

Togamycin H2O Solubility


Togamycin State


Togamycin LogP


Togamycin Dosage Forms

Cream or gel (0.05% or 0.1%)

Togamycin Indication

Used to treat psoriasis, acne and sun damaged skin (photodamage).

Togamycin Pharmacology

Tazarotene is a prodrug and a member of the acetylenic class of retinoids. Following topical application, tazarotene undergoes esterase hydrolysis to form its active metabolite, tazarotenic acid. When treating acne tazarotene may be taken in conjunction with an oral antibiotic. Tazarotene has been shown in peer-reviewed double blinded studies to reduce: mottling and hyperpigmentation, sallowness, fine wrinkling and coarse wrinkling in sun damaged skin. Histological studies have shown that long term (greater than 1 year) use of Tazarotene is associated with a significant reduction in atypical melanocytes and keratocytes - cells considered to be precursors of skin cancer. Some studies have shown long term use of Tazarotene to be associated with increased collagen production and better organization of skin collagen bundles.

Togamycin Absorption

Minimal systemic absorption of tazarotene occurs due to its rapid metabolism in the skin to the active metabolite, tazarotenic acid, which can be systemically absorbed and further metabolized. Gender had no influence on the systemic bioavailability of tazarotenic acid.

Togamycin side effects and Toxicity

Excessive topical use may lead to marked redness, peeling, or discomfort. Oral ingestion of the drug may affect liver function causing hypertriglyceridemia. Other symptoms may include conjunctival irritation, hair loss, headache, edema, fatigue, dermatitis, nausea, and visual disturbances. Oral administration of this material to rats and rabbits at doses of 0.20 mg/kg/day (rabbits) and 0.25 mg/kg/day (rats) resulted in developmental toxicity. A no effect level of 0.05 mg/kg/day was established. Similar teratogenic effects have been reported for other retinoid compounds.

Togamycin Patient Information

Togamycin Organisms Affected

Humans and other mammals