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Ticlopidine Brand names, Ticlopidine Analogs

Ticlopidine Brand Names Mixture

  • No information avaliable

Ticlopidine Chemical_Formula


Ticlopidine RX_link


Ticlopidine fda sheet

Ticlopidine FDA

Ticlopidine msds (material safety sheet)

Ticlopidine MSDS

Ticlopidine Synthesis Reference

No information avaliable

Ticlopidine Molecular Weight

263.786 g/mol

Ticlopidine Melting Point

No information avaliable

Ticlopidine H2O Solubility

Freely soluble

Ticlopidine State


Ticlopidine LogP


Ticlopidine Dosage Forms

Tablets (for oral administration, containing 250 mg of ticlopidine hydrochloride)

Ticlopidine Indication

Used to reduce the risk of thrombotic stroke (fatal or nonfatal) in patients who have experienced stroke precursors, and in patients who have had a completed thrombotic stroke.

Ticlopidine Pharmacology

Ticlopidine is a platelet aggregation inhibitor structurally and pharmacologically similar to clopidogrel. When taken orally, ticlopidine causes a time- and dose-dependent inhibition of both platelet aggregation and release of platelet granule constituents, as well as a prolongation of bleeding time. The intact drug has no significant in vitro activity at the concentrations attained in vivo; and, although analysis of urine and plasma indicates at least 20 metabolites, no metabolite which accounts for the activity of ticlopidine has been isolated.

Ticlopidine Absorption

Absorption is greater than 80%. Food increases absorption.

Ticlopidine side effects and Toxicity

Single oral doses of ticlopidine at 1600 mg/kg and 500 mg/kg were lethal to rats and mice, respectively. Symptoms of acute toxicity were GI hemorrhage, convulsions, hypothermia, dyspnea, loss of equilibrium and abnormal gait.

Ticlopidine Patient Information

Ticlopidine Organisms Affected

Humans and other mammals