Thioseconal
Brand names,
Thioseconal
Analogs
Thioseconal
Brand Names Mixture
Thioseconal
Chemical_Formula
C12H18N2O2S
Thioseconal
RX_link
No information avaliable
Thioseconal
fda sheet
Thioseconal
msds (material safety sheet)
Thioseconal
Synthesis Reference
No information avaliable
Thioseconal
Molecular Weight
254.35 g/mol
Thioseconal
Melting Point
132-133 oC
Thioseconal
H2O Solubility
49.4 mg/L
Thioseconal
State
Solid
Thioseconal
LogP
2.848
Thioseconal
Dosage Forms
Powder for solution
Thioseconal
Indication
Used for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state.
Thioseconal
Pharmacology
Thiamylal, a barbiturate, is used in combination with acetaminophen or aspirin and caffeine for its sedative and relaxant effects in the treatment of tension headaches, migraines, and pain. Barbiturates act as nonselective depressants of the central nervous system (CNS), capable of producing all levels of CNS mood alteration from excitation to mild sedation, hypnosis, and deep coma. In sufficiently high therapeutic doses, barbiturates induce anesthesia.
Thioseconal
Absorption
Rapidly absorbed (high lipid solubility).
Thioseconal
side effects and Toxicity
Intravenous LD50 in rat is 51 mg/kg.
Thioseconal
Patient Information
No information avaliable
Thioseconal
Organisms Affected
Humans and other mammals