Surital
Brand names,
Surital
Analogs
Surital
Brand Names Mixture
Surital
Chemical_Formula
C12H18N2O2S
Surital
RX_link
No information avaliable
Surital
fda sheet
Surital
msds (material safety sheet)
Surital
Synthesis Reference
No information avaliable
Surital
Molecular Weight
254.35 g/mol
Surital
Melting Point
132-133 oC
Surital
H2O Solubility
49.4 mg/L
Surital
State
Solid
Surital
LogP
2.848
Surital
Dosage Forms
Powder for solution
Surital
Indication
Used for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state.
Surital
Pharmacology
Thiamylal, a barbiturate, is used in combination with acetaminophen or aspirin and caffeine for its sedative and relaxant effects in the treatment of tension headaches, migraines, and pain. Barbiturates act as nonselective depressants of the central nervous system (CNS), capable of producing all levels of CNS mood alteration from excitation to mild sedation, hypnosis, and deep coma. In sufficiently high therapeutic doses, barbiturates induce anesthesia.
Surital
Absorption
Rapidly absorbed (high lipid solubility).
Surital
side effects and Toxicity
Intravenous LD50 in rat is 51 mg/kg.
Surital
Patient Information
No information avaliable
Surital
Organisms Affected
Humans and other mammals