Tamiflu
Brand names,
Tamiflu
Analogs
Tamiflu
Brand Names Mixture
Tamiflu
Chemical_Formula
C48H74O14
Tamiflu
RX_link
http://www.rxlist.com/cgi/generic3/ivermectin.htm
Tamiflu
fda sheet
Tamiflu
msds (material safety sheet)
Tamiflu
Synthesis Reference
No information avaliable
Tamiflu
Molecular Weight
875.10 g/mol
Tamiflu
Melting Point
155 oC
Tamiflu
H2O Solubility
Insoluble
Tamiflu
State
Solid
Tamiflu
LogP
6.704
Tamiflu
Dosage Forms
Bolus; Liquid; Solution; Tablet
Tamiflu
Indication
For the treatment of intestinal (i.e., nondisseminated) strongyloidiasis due to the nematode parasite Strongyloides stercoralis. Also for the treatment of onchocerciasis (river blindness) due to the nematode parasite Onchocerca volvulus. Can be used to treat scabies caused by Sarcoptes scabiei.
Tamiflu
Pharmacology
Ivermectin is a semisynthetic, anthelminitic agent. It is an avermectin which a group of pentacyclic sixteen-membered lactone (i.e. a macrocyclic lactone disaccharide) derived from the soil bacterium Streptomyces avermitilis. Avermectins are potent anti-parasitic agents. Ivermectin is the most common avermectin. It is a broad spectrum antiparasitic drug for oral administration. It is sometimes used to treat human onchocerciasis (river blindness). It is the mixture of 22,23-dihydro-avermectin B1a (at least 90%) and 22,23-dihydro-avermectin B1b (less than 10%).
Tamiflu
Absorption
Moderately well absorbed. Improved absorption with high fat meal.
Tamiflu
side effects and Toxicity
LD50 29.5 mg/kg (Mouse, oral). LD50 10 mg/kg (Rat, oral). Adverse effects include muscle or joint pain, dizziness, fever, headache, skin rash, fast heartbeat.
Tamiflu
Patient Information
http://www.drugs.com/MTM/isoniazid.html
Tamiflu
Organisms Affected
Parasitic nematodes and other roundworms