Oseltamivir
Brand names,
Oseltamivir
Analogs
Oseltamivir
Brand Names Mixture
Oseltamivir
Chemical_Formula
C48H74O14
Oseltamivir
RX_link
http://www.rxlist.com/cgi/generic3/ivermectin.htm
Oseltamivir
fda sheet
Oseltamivir
msds (material safety sheet)
Oseltamivir
Synthesis Reference
No information avaliable
Oseltamivir
Molecular Weight
875.10 g/mol
Oseltamivir
Melting Point
155 oC
Oseltamivir
H2O Solubility
Insoluble
Oseltamivir
State
Solid
Oseltamivir
LogP
6.704
Oseltamivir
Dosage Forms
Bolus; Liquid; Solution; Tablet
Oseltamivir
Indication
For the treatment of intestinal (i.e., nondisseminated) strongyloidiasis due to the nematode parasite Strongyloides stercoralis. Also for the treatment of onchocerciasis (river blindness) due to the nematode parasite Onchocerca volvulus. Can be used to treat scabies caused by Sarcoptes scabiei.
Oseltamivir
Pharmacology
Ivermectin is a semisynthetic, anthelminitic agent. It is an avermectin which a group of pentacyclic sixteen-membered lactone (i.e. a macrocyclic lactone disaccharide) derived from the soil bacterium Streptomyces avermitilis. Avermectins are potent anti-parasitic agents. Ivermectin is the most common avermectin. It is a broad spectrum antiparasitic drug for oral administration. It is sometimes used to treat human onchocerciasis (river blindness). It is the mixture of 22,23-dihydro-avermectin B1a (at least 90%) and 22,23-dihydro-avermectin B1b (less than 10%).
Oseltamivir
Absorption
Moderately well absorbed. Improved absorption with high fat meal.
Oseltamivir
side effects and Toxicity
LD50 29.5 mg/kg (Mouse, oral). LD50 10 mg/kg (Rat, oral). Adverse effects include muscle or joint pain, dizziness, fever, headache, skin rash, fast heartbeat.
Oseltamivir
Patient Information
http://www.drugs.com/MTM/isoniazid.html
Oseltamivir
Organisms Affected
Parasitic nematodes and other roundworms