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Sulindac Brand names, Sulindac Analogs

Sulindac Brand Names Mixture

  • No information avaliable

Sulindac Chemical_Formula

C20H17FO3S

Sulindac RX_link

http://www.rxlist.com/cgi/generic3/sulindac.htm

Sulindac fda sheet

Sulindac msds (material safety sheet)

Sulindac MSDS

Sulindac Synthesis Reference

No information avaliable

Sulindac Molecular Weight

356.412 g/mol

Sulindac Melting Point

183 oC

Sulindac H2O Solubility

Pactically insoluble in water below pH 4.5, but very soluble as the sodium salt or in buffers of pH 6 or higher (3000 mg/L).

Sulindac State

Solid

Sulindac LogP

2.693

Sulindac Dosage Forms

150 and 200 mg tablets for oral administration

Sulindac Indication

For acute or long-term use in the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis. ankylosing spondylitis, acute painful shoulder (acute subacromial bursitis/supraspinatus tendinitis), and acute gouty arthritis.

Sulindac Pharmacology

Sulindac is a non-steroidal anti-inflammatory indene derivative, also possessing analgesic and antipyretic activities.

Sulindac Absorption

Approximately 90% absorbed in man following oral administration.

Sulindac side effects and Toxicity

Acute oral toxicity (LD50) in rats is 264 mg/kg. Cases of overdosage have been reported and rarely, deaths have occurred. The following signs and symptoms may be observed following overdosage: stupor, coma, diminished urine output and hypotension.

Sulindac Patient Information

No information avaliable

Sulindac Organisms Affected

Humans and other mammals