Sulindac

Sulindac Brand names, Sulindac Analogs

Zagam

Sulindac Brand Names Mixture

No information avaliable

Sulindac Chemical_Formula

C₂₀H₁₇FO₃S

Sulindac RX_link

http://www.rxlist.com/cgi/generic3/sulindac.htm

Sulindac fda sheet

Sulindac msds (material safety sheet)

Sulindac MSDS

Sulindac Synthesis Reference

No information avaliable

Sulindac Molecular Weight

356.412 g/mol

Sulindac Melting Point

183 ^oC

Sulindac H₂O Solubility

Pactically insoluble in water below pH 4.5, but very soluble as the sodium salt or in buffers of pH 6 or higher (3000 mg/L).

Sulindac State

Solid

Sulindac LogP

2.693

Sulindac Dosage Forms

150 and 200 mg tablets for oral administration

Sulindac Indication

For acute or long-term use in the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis. ankylosing spondylitis, acute painful shoulder (acute subacromial bursitis/supraspinatus tendinitis), and acute gouty arthritis.

Sulindac Pharmacology

Sulindac is a non-steroidal anti-inflammatory indene derivative, also possessing analgesic and antipyretic activities.

Sulindac Absorption

Approximately 90% absorbed in man following oral administration.

Sulindac side effects and Toxicity

Acute oral toxicity (LD₅₀) in rats is 264 mg/kg. Cases of overdosage have been reported and rarely, deaths have occurred. The following signs and symptoms may be observed following overdosage: stupor, coma, diminished urine output and hypotension.

Sulindac Patient Information