Zagam

Zagam Brand names, Zagam Analogs

Zagam

Zagam Brand Names Mixture

No information avaliable

Zagam Chemical_Formula

C₂₀H₁₇FO₃S

Zagam RX_link

http://www.rxlist.com/cgi/generic3/sulindac.htm

Zagam fda sheet

Zagam msds (material safety sheet)

Zagam MSDS

Zagam Synthesis Reference

No information avaliable

Zagam Molecular Weight

356.412 g/mol

Zagam Melting Point

183 ^oC

Zagam H₂O Solubility

Pactically insoluble in water below pH 4.5, but very soluble as the sodium salt or in buffers of pH 6 or higher (3000 mg/L).

Zagam State

Solid

Zagam LogP

2.693

Zagam Dosage Forms

150 and 200 mg tablets for oral administration

Zagam Indication

For acute or long-term use in the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis. ankylosing spondylitis, acute painful shoulder (acute subacromial bursitis/supraspinatus tendinitis), and acute gouty arthritis.

Zagam Pharmacology

Sulindac is a non-steroidal anti-inflammatory indene derivative, also possessing analgesic and antipyretic activities.

Zagam Absorption

Approximately 90% absorbed in man following oral administration.

Zagam side effects and Toxicity

Acute oral toxicity (LD₅₀) in rats is 264 mg/kg. Cases of overdosage have been reported and rarely, deaths have occurred. The following signs and symptoms may be observed following overdosage: stupor, coma, diminished urine output and hypotension.

Zagam Patient Information