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Brand names,
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Analogs
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Brand Names Mixture
- Diophenyl-T Solution (Phenylephrine Hydrochloride + Tropicamide)
- Phenyltrope Oph Soln (Phenylephrine Hydrochloride + Tropicamide)
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Chemical_Formula
C17H20N2O2
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
284.353 g/mol
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Melting Point
96.5 oC
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H2O Solubility
No information avaliable
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State
Solid
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LogP
2.182
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Dosage Forms
Drops; Liquid; Solution
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Indication
Indicated to induce mydriasis (dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) in diagnostic procedures, such as measurement of refractive errors and examination of the fundus of the eye.
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Pharmacology
Tropicamide belongs to the group of medicines called anti-muscarinics. Tropicamide blocks the receptors in the muscles of the eye (muscarinic receptors). These receptors are involved controlling the pupil size and the shape of the lens. By blocking these receptors, tropicamide produces dilatation of the pupil (mydriasis) and prevents the eye from accommodating for near vision (cycloplegia). Tropicamide is given as eye drops to dilate the pupil and relax the lens so that eye examinations can be carried out thoroughly.
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Absorption
No information avaliable
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side effects and Toxicity
Overdose can casue dry mouth, blurred vision, photophobia, hallucinations and rapid/irregular pulse.
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Patient Information
This medication is for use in the eye. One or two drops are placed in the eye(s) 15 minutes or so prior to examination. Additional drops may be necessary to achieve the desired effect for an eye examination. When used to treat eye conditions, use as directed by your prescriber for the full course of treatment. After application of the drops, apply pressure to the side of the nose where the tear duct is with your finger for 1 to 3 minutes to prevent absorption into the body.
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Organisms Affected
Humans and other mammals