I-Picamide
Brand names,
I-Picamide
Analogs
I-Picamide
Brand Names Mixture
- Diophenyl-T Solution (Phenylephrine Hydrochloride + Tropicamide)
- Phenyltrope Oph Soln (Phenylephrine Hydrochloride + Tropicamide)
I-Picamide
Chemical_Formula
C17H20N2O2
I-Picamide
RX_link
No information avaliable
I-Picamide
fda sheet
I-Picamide
msds (material safety sheet)
I-Picamide
Synthesis Reference
No information avaliable
I-Picamide
Molecular Weight
284.353 g/mol
I-Picamide
Melting Point
96.5 oC
I-Picamide
H2O Solubility
No information avaliable
I-Picamide
State
Solid
I-Picamide
LogP
2.182
I-Picamide
Dosage Forms
Drops; Liquid; Solution
I-Picamide
Indication
Indicated to induce mydriasis (dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) in diagnostic procedures, such as measurement of refractive errors and examination of the fundus of the eye.
I-Picamide
Pharmacology
Tropicamide belongs to the group of medicines called anti-muscarinics. Tropicamide blocks the receptors in the muscles of the eye (muscarinic receptors). These receptors are involved controlling the pupil size and the shape of the lens. By blocking these receptors, tropicamide produces dilatation of the pupil (mydriasis) and prevents the eye from accommodating for near vision (cycloplegia). Tropicamide is given as eye drops to dilate the pupil and relax the lens so that eye examinations can be carried out thoroughly.
I-Picamide
Absorption
No information avaliable
I-Picamide
side effects and Toxicity
Overdose can casue dry mouth, blurred vision, photophobia, hallucinations and rapid/irregular pulse.
I-Picamide
Patient Information
This medication is for use in the eye. One or two drops are placed in the eye(s) 15 minutes or so prior to examination. Additional drops may be necessary to achieve the desired effect for an eye examination. When used to treat eye conditions, use as directed by your prescriber for the full course of treatment. After application of the drops, apply pressure to the side of the nose where the tear duct is with your finger for 1 to 3 minutes to prevent absorption into the body.
I-Picamide
Organisms Affected
Humans and other mammals